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Gene expression patterns in visual cortex during the critical period: Synaptic stabilization and reversal by visual deprivation
(National Academy of Sciences, 2008-07)
The mapping of eye-specific, geniculocortical inputs to primary visual cortex (V1) is highly sensitive to the balance of correlated activity between the two eyes during a restricted postnatal critical period for ocular ...
Policy Adjustment in a Dynamic Economic Game
(PLOS, 2006-12)
Making sequential decisions to harvest rewards is a notoriously difficult problem. One difficulty is that the real world is not stationary and the reward expected from a contemplated action may depend in complex ways on ...
Molecular mechanisms of experience-dependent plasticity in visual cortex
(Royal Society, 2008)
A remarkable amount of our current knowledge of mechanisms underlying experience-dependent plasticity during cortical development comes from study of the mammalian visual cortex. Recent advances in high-resolution cellular ...
Neural responses to sanction threats in two-party economic exchange
(NAS, 2009-08-11)
Sanctions are used ubiquitously to enforce obedience to social norms. However, recent field studies and laboratory experiments have demonstrated that cooperation is sometimes reduced when incentives meant to promote prosocial ...
Congruence of BOLD Response across Intertemporal Choice Conditions: Fictive and Real Money Gains and Losses
(Society for Neuroscience, 2009-07-08)
Intertemporal choice is predicated on the valuation of commodities with respect to delay until their receipt. Subjective value of a future outcome decreases, or is discounted, as a function of that delay (Bickel and Johnson, ...
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
(The Rockefeller University Press, 2008-09-15)
A prominent feature of synaptic maturation at the neuromuscular junction (NMJ) is the topological transformation of the acetylcholine receptor (AChR)-rich postsynaptic membrane from an ovoid plaque into a complex array of ...
Remote Excitation of Neuronal Circuits Using Low- Intensity, Low-Frequency Ultrasound
(PLOS, 2008-10-29)
Possessing the ability to noninvasively elicit brain circuit activity yields immense experimental and therapeutic power. Most currently employed neurostimulation methods rely on the somewhat invasive use of stimulating ...
Ready…Go: Amplitude of the fMRI Signal Encodes Expectation of Cue Arrival Time
(PLOS, 2009-08-04)
What happens when the brain awaits a signal of uncertain arrival time, as when a sprinter waits for the starting pistol? And what happens just after the starting pistol fires? Using functional magnetic resonance imaging ...
Dendritic Spikes and Their Influence on Extracellular Calcium Signaling
(American Physiological Society, 2000)
Extracellular calcium is critical for many neural functions, including neurotransmission, cell adhesion, and neural plasticity. Experiments have shown that normal neural activity is associated with changes in extracellular ...
When Things Are Better or Worse than Expected: The Medial Frontal Cortex and the Allocation of Processing Resources
(MIT, 2006)
Access to limited-capacity neural systems of cognitive control must be restricted to the most relevant information. How the brain identifies and selects items for preferential processing is not fully understood. Anatomical ...