Now showing items 1-4 of 4
Neuroeconomic measures of social decision-making across the lifespan
Social and decision-making deficits are often the first symptoms of a striking number of neurodegenerative disorders associated with aging.These includes not only disorders that directly impact dopamine and basal ganglia, ...
Attenuating Cholinergic Transmission Increases the Number of Satellite Cells and Preserves Muscle Mass in Old Age
In addition to driving contraction of skeletal muscles, acetylcholine (ACh) acts as an anti-synaptogenic agent at neuromuscular junctions (NMJs). Previous studies suggest that aging is accompanied by increases in cholinergic ...
Aging into Perceptual Control: A Dynamic Causal Modeling for fMRI Study of Bistable Perception
Aging is accompanied by stereotyped changes in functional brain activations, for example a cortical shift in activity patterns from posterior to anterior regions is one hallmark revealed by functional magnetic resonance ...
𝛼-Motor neurons are spared from aging while their synaptic inputs degenerate in monkeys and mice
Motor function deteriorates with advancing age, increasing the risk of adverse health outcomes. While it is well established that skeletal muscles and neuromuscular junctions (NMJs) degenerate with increasing age, the ...