Browsing Scholarly Works, School of Biomedical Engineering and Sciences by Title
Now showing items 28-47 of 132
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Effect of Localized Mechanical Indentation on Skin Water Content Evaluated Using OCT
(Hindawi, 2011-08-04)The highly disordered refractive index distribution in skin causes multiple scattering of incident light and limits optical imaging and therapeutic depth. We hypothesize that localized mechanical compression reduces ... -
Effects of acute ingestion of different fats on oxidative stress and inflammation in overweight and obese adults.
(2011-11-07)Background Studies show that obese individuals have prolonged elevations in postprandial lipemia and an exacerbated inflammatory response to high fat meals, which can increase risk for cardiovascular diseases. As ... -
Effects of receptor clustering on ligand dissociation kinetics: Theory and simulations
(CELL PRESS, 2005-12-01)Receptor-ligand binding is a critical first step in signal transduction and the duration of the interaction can impact signal generation. In mammalian cells, clustering of receptors may be facilitated by heterogeneous zones ... -
Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties
(Hindawi, 2009-07-09)Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex ... -
Electrochemotherapy (ECT) and irreversible electroporation (IRE) -advanced techniques for treating deep-seated tumors based on electroporation
(2015-08-27)When a cell is exposed to a sufficiently intense electric field (for a sufficient duration), local defects in the cell membrane appear and become permeable to molecules that otherwise cannot pass through it. This phenomenon ... -
Electroporation-based delivery of cell-penetrating peptide conjugates of peptide nucleic acids for antisense inhibition of intracellular bacteria
(The Royal Society of Chemistry, 2014-08-14)Cell penetrating peptides (CPPs) have been used for a myriad of cellular delivery applications and were recently explored for delivery of antisense agents such as peptide nucleic acids (PNAs) for bacterial inhibition. ... -
Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding
(The Royal Society of Chemistry, 2014-08-08)Fluorescent protein biosensors are typically implemented via genetic encoding which makes the examination of scarce cell samples impractical. By directly delivering the protein form of the biosensor into cells using ... -
Endothelial cell sensing, restructuring, and invasion in collagen hydrogel structures
(The Royal Society of Chemistry, 2015-09-03)Experimental tools to model cell-tissue interactions will likely lead to new ways to both understand and treat cancer. While the mechanical properties and regulation of invasion have been recently studied for tumor cells, ... -
Enduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury
(Nature Publishing Group, 2015-11-05) -
Evaluation of Two Approaches for Aligning Data Obtained from a Motion Capture System and an In-Shoe Pressure Measurement System
(MDPI, 2014-09-12)An in-shoe pressure measurement (IPM) system can be used to measure center of pressure (COP) locations, and has fewer restrictions compared to the more conventional approach using a force platform. The insole of an IPM ... -
Exact Interior Reconstruction from Truncated Limited-Angle Projection Data
(Hindawi, 2008-05-06)Using filtered backprojection (FBP) and an analytic continuation approach, we prove that exact interior reconstruction is possible and unique from truncated limited-angle projection data, if we assume a prior knowledge on ... -
Exact Interior Reconstruction with Cone-Beam CT
(Hindawi, 2008-01-23)Using the backprojection filtration (BPF) and filtered backprojection (FBP) approaches, respectively, we prove that with cone-beam CT the interior problem can be exactly solved by analytic continuation. The prior knowledge ... -
Experimental Study on Bioluminescence Tomography with Multimodality Fusion
(Hindawi, 2007-09-10)To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncontact detection mode, ... -
Fabrication and Characterization of Three Dimensional Electrospun Cortical Bone Scaffolds
(De Gruyter Open, 2014)Bone is a composite tissue composed of an organic matrix, inorganic mineral matrix and water. Structurally, bone is organized into two distinct types: trabecular (or cancellous) and cortical (or compact) bone. Cortical ... -
A Fast CT Reconstruction Scheme for a General Multi-Core PC
(Hindawi, 2007-07-04)Expensive computational cost is a severe limitation in CT reconstruction for clinical applications that need real-time feedback. A primary example is bolus-chasing computed tomography (CT) angiography (BCA) that we have ... -
Flow Measurements in a Blood-Perfused Collagen Vessel Using X-Ray Micro-Particle Image Velocimetry
(2013-11-18)Blood-perfused tissue models are joining the emerging field of tumor engineering because they provide new avenues for modulation of the tumor microenvironment and preclinical evaluation of the therapeutic potential of new ... -
Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability
(PLOS, 2018-03-22)Ovarian cancer cells are exposed to physical stress in the peritoneal cavity during both tumor growth and dissemination. Ascites build-up in metastatic ovarian cancer further increases the exposure to fluid shear stress. ... -
Folate Conjugated Cellulose Nanocrystals Potentiate Irreversible Electroporation-induced Cytotoxicity for the Selective Treatment of Cancer Cells
(Adenine Press, 2014-04-16)Cellulose nanocrystals are rod-shaped, crystalline nanoparticles that have shown prom- ise in a number of industrial applications for their unique chemical and physical properties. However, investigations of their abilities ... -
Folic Acid-Conjugated Cellulose Nanocrystals Show High Folate-Receptor Binding Affinity and Uptake by KB and Breast Cancer Cells
(American Chemical Society, 2018-10-24)The study evaluates cellulose nanocrystals (CNCs) as nanocarriers for targeted, intracellular delivery of molecular agents. CNCs were labeled with fluorescein-5′-isothiocyanate as an imaging agent and conjugated to folic ... -
Frame-Based Stereotactic Biopsy of Canine Brain Masses: Technique and Clinical Results in 26 Cases
(2015)This report describes the methodology, diagnostic yield, and adverse events (AE) associated with frame-based stereotactic brain biopsies (FBSB) obtained from 26 dogs with solitary forebrain lesions. Medical records were ...
