The Virginia Tech-Wake Forest University School of Biomedical Engineering & Sciences (SBES) is a joint graduate program formed in 2003 to bring together three prestigious academic institutions: the College of Engineering at Virginia Tech, the Wake Forest University School of Medicine, and the Regional Virginia-Maryland College of Veterinary Medicine. On August 11, 2014, Virginia Tech announced a new collaboration between SBES and the Engineering Science and Mechanics department to form the new Department of Biomedical Engineering and Mechanics. This department provides a strong foundation and a sturdy framework for the discovery, development, transfer, and implementation of new knowledge in the areas of mechanics of materials and material systems, fluid mechanics, dynamics and vibration, biomechanics, and computational methods. The department is fully committed to providing an environment for strong undergraduate and graduate education that emphasizes fundamental understanding rather than specialization, high-quality teaching, innovation, frontier-level research, and service to the professional mechanics community.

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Recent Submissions

  • Electrotaxis-on-Chip to Quantify Neutrophil Migration Towards Electrochemical Gradients 

    Moarefian, Maryam; Davalos, Rafael V.; Burton, Michael D.; Jones, Caroline N. (2021-08-06)
    Electric fields are generated in vivo in a variety of physiologic and pathologic settings, including wound healing and immune response to injuries to epithelial barriers (e.g. lung pneumocytes). Immune cells are known to ...
  • Automated Movement Assessment in Stroke Rehabilitation 

    Ahmed, Tamim; Thopalli, Kowshik; Rikakis, Thanassis; Turaga, Pavan; Kelliher, Aisling; Huang, Jia-Bin; Wolf, Steven L. (2021-08-19)
    We are developing a system for long term Semi-Automated Rehabilitation At the Home (SARAH) that relies on low-cost and unobtrusive video-based sensing. We present a cyber-human methodology used by the SARAH system for ...
  • Cellular Size, Gap Junctions, and Sodium Channel Properties Govern Developmental Changes in Cardiac Conduction 

    Nowak, Madison B.; Veeraraghavan, Rengasayee; Poelzing, Steven; Weinberg, Seth H. (2021-10-25)
    Electrical conduction in cardiac ventricular tissue is regulated via sodium (Na+) channels and gap junctions (GJs). We and others have recently shown that Na(+)channels preferentially localize at the site of cell-cell ...
  • A 3-D Finite-Element Minipig Model to Assess Brain Biomechanical Responses to Blast Exposure 

    Sundaramurthy, Aravind; Kote, Vivek Bhaskar; Pearson, Noah; Boiczyk, Gregory M.; McNeil, Elizabeth M.; Nelson, Allison J.; Subramaniam, Dhananjay Radhakrishnan; Rubio, Jose E.; Monson, Kenneth; Hardy, Warren N.; VandeVord, Pamela J.; Unnikrishnan, Ginu; Reifman, Jaques (Frontiers, 2021-12-17)
    Despite years of research, it is still unknown whether the interaction of explosion-induced blast waves with the head causes injury to the human brain. One way to fill this gap is to use animal models to establish “scaling ...
  • Development of a Minipig Model of BINT From Blast Exposure Using a Repeatable Mobile Shock Expansion Tube 

    McNeil, Elizabeth M.; Walilko, Timothy; Hulbert, Lindsey E.; VanMeter, John W.; LaConte, Stephen M.; VandeVord, Pamela J.; Zai, Laila; Bentley, Timothy B. (Oxford University Press, 2021-10-22)
    Introduction: The Office of Naval Research (ONR) sponsored the Blast Load Assessment Sense and Test (BLAST) program to provide an approach to operationally relevant monitoring and analysis of blast exposure for optimization ...
  • Insect Microfluidics: Hearing and Breathing While Tiny 

    Staples, Anne E.; Mikel-Stites, Maxwell (IUTAM, 2021-08-27)
    Insects have evolved to handle fluids using strategies that vary significantly from those used by larger animals since, by virtue of their size, they interact with fluids in the microscale regime, where surface forces ...
  • Research Trends in Biological Fluid Dynamics 

    Jung, Sunny; Staples, Anne E.; Dabiri, John O.; Marsden, Alison L.; Prakash, Manu; Davis, Kristen A.; Shadden, Shawn C.; Savin, Thierry; Bourouiba, Lydia; Sznitman, Josue (National Academies, 2015-01-01)
  • Nonlinear one-dimensional constitutive model for magnetostrictive materials 

    Imhof, Alecsander N.; Domann, John P. (2022-02-08)
    This paper presents an analytic model of one dimensional magnetostriction. We show how specific assumptions regarding the symmetry of key micromagnetic energies (magnetocrystalline, magnetoelastic, and Zeeman) reduce a ...
  • Snow Sport Helmet STAR Protocol 

    Keim, Summer; Begonia, Mark T.; Kieffer, Emily E.; Rowson, Steven (Virginia Tech, 2022-02-11)
    This document details the protocol used by the Virginia Tech Helmet Ratings to rate snow sport helmets based on concussion risk.
  • Hockey STAR Methodology 

    Begonia, Mark T.; Tyson, Abigail M.; Rowson, Bethany M.; Rowson, Steven (Virginia Tech, 2022-02-08)
    This document details the protocol used by the Virginia Tech Helmet Ratings to rate hockey helmets based on concussion risk.
  • Implementing Head Impact Sensors in Collegiate Men’s and Women’s Rugby: Successes and Challenges in Characterizing Concussion 

    Kieffer, Emily E.; Rowson, Steven (Virginia Tech, 2022-01-29)
    Head impact sensors allow researchers to learn more about human tolerance to head impact exposure and concussion. Previous on-field data collection has worked to quantify concussion biomechanics, based primarily on helmeted ...
  • Virginia Tech Hockey Helmet Ratings Memorandum 

    Rowson, Steven; Begonia, Mark T.; Rowson, Bethany M.; Duma, Stefan M. (Virginia Tech, 2022-01-25)
    This memorandum serves to reiterate the goals of the Virginia Tech Helmet Ratings, discuss the hockey helmet ratings, and announce an update to the exposure weightings and star thresholds used to rate hockey helmets.
  • An Investigation for Large Volume, Focal Blood-Brain Barrier Disruption with High-Frequency Pulsed Electric Fields 

    Lorenzo, Melvin F.; Campelo, Sabrina N.; Arroyo, Julio P.; Aycock, Kenneth N.; Hinckley, Jonathan; Arena, Christopher B.; Rossmeisl, John H. Jr.; Davalos, Rafael V. (MDPI, 2021-12-20)
    The treatment of CNS disorders suffers from the inability to deliver large therapeutic agents to the brain parenchyma due to protection from the blood-brain barrier (BBB). Herein, we investigated high-frequency pulsed ...
  • Early influences of microbiota on white matter development in germ-free piglets 

    Ahmed, Sadia; Travis, Sierrah; Díaz-Bahamonde, Francisca; Porter, Demisha; Henry, Sara; Ravipati, Aditya; Booker, Aryn; Ding, Hanzhang; Ju, Jing; Ramesh, Ashwin; Pickrell, Alicia M.; Wang, Maosen; LaConte, Stephen M.; Howell, Brittany R.; Yuan, Lijuan; Morton, Paul D. (Frontiers, 2021-12-27)
    Abnormalities in the prefrontal cortex (PFC), as well as the underlying white matter (WM) tracts, lie at the intersection of many neurodevelopmental disorders. The influence of microorganisms on brain development has ...
  • Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma 

    Dickerson, Michelle R.; Murphy, Susan F.; Urban, Michael J.; White, Zakar; VandeVord, Pamela J. (Frontiers, 2021-12-10)
    Long-term neuropsychiatric impairments have become a growing concern following blast-related traumatic brain injury (bTBI) in active military personnel and Veterans. Neuropsychiatric impairments such as anxiety and depression ...
  • Modeling Immunity In Vitro: Slices, Chips, and Engineered Tissues 

    Hammel, Jennifer H.; Cook, Sophie R.; Belanger, Maura C.; Munson, Jennifer M.; Pompano, Rebecca R. (Annual Reviews, 2021-07)
    Modeling immunity in vitro has the potential to be a powerful tool for investigating fundamental biological questions, informing therapeutics and vaccines, and providing new insight into disease progression. There are two ...
  • A Validated Hip Finite Element Model for Simulating Pedestrian Accidents 

    Untaroiu, Costin D.; Grindle, Daniel M. (2021-10-07)
  • A finite element of an electric scooter model for simulating traffic accidents 

    Chontos, Rafael; Grindle, Daniel M.; Untaroiu, Alexandrina; Untaroiu, Costin D. (2021-10-07)
  • STAR Methodology for Rugby Headgear 

    Kieffer, Emily E.; Rowson, Steven (Virginia Tech, 2021-07-13)
    This document details the protocol used to rate rugby headgear based on concussion risk according to the Virginia Tech Helmet Ratings.
  • Large-Eddy Simulation of a Hydrocyclone with an Air Core Using Two-Fluid and Volume-of-Fluid Models 

    Fayed, Hassan; Bukhari, Mustafa; Ragab, Saad A. (MDPI, 2021-10-14)
    Large-eddy simulations have been conducted for two-phase flow (water and air) in a hydrocyclone using Two-Fluid (Euler–Euler) and Volume-of-Fluid (VOF) models. Subgrid stresses are modeled using a dynamic eddy–viscosity ...

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