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Now showing items 11-12 of 12
Quantification of total T-cell receptor diversity by flow cytometry and spectratyping
(Biomed Central Ltd, 2013-08-06)
Background T-cell receptor diversity correlates with immune competency and is of particular interest in patients undergoing immune reconstitution. Spectratyping generates data about T-cell receptor CDR3 length distribution ...
Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model
(Biomed Central Ltd, 2013-06-28)
Background 'Parameter estimation from experimental data is critical for mathematical modeling of protein regulatory networks. For realistic networks with dozens of species and reactions, parameter estimation is an especially ...