Browsing Scholarly Works, Department of Chemical Engineering by Title
Now showing items 1-20 of 109
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3D Hepatic Cultures Simultaneously Maintain Primary Hepatocyte and Liver Sinusoidal Endothelial Cell Phenotypes
(PLOS, 2010-11-12)Developing in vitro engineered hepatic tissues that exhibit stable phenotype is a major challenge in the field of hepatic tissue engineering. However, the rapid dedifferentiation of hepatic parenchymal (hepatocytes) and ... -
Ambient ammonia synthesis via palladium-catalyzed electrohydrogenation of dinitrogen at low overpotential
(Springer Nature, 2018-05-15)Electrochemical reduction of N2 to NH3 provides an alternative to the Haber−Bosch process for sustainable, distributed production of NH3 when powered by renewable electricity. However, the development of such process has ... -
Ammonium Bisphosphonate Polymeric Magnetic Nanocomplexes for Platinum Anticancer Drug Delivery and Imaging with Potential Hyperthermia and Temperature-Dependent Drug Release
(Hindawi, 2018-08-05)Novel magnetite-ammonium bisphosphonate graft ionic copolymer nanocomplexes (MGICs) have been developed for potential drug delivery, magnetic resonance imaging, and hyperthermia applications. The complexes displayed ... -
Anticancer nanoparticulate polymer-drug conjugate
(Wiley, 2016-08-26)We review recent progress in polymer-drug conjugate for cancer nanomedicine. Polymer-drug conjugates, including the nanoparticle prepared from these conjugates, are designed to release drug in tumor tissues or cells in ... -
The assembly of integrated rat intestinal-hepatocyte cultures
(2019-11)The jejunum is the segment of the small intestine responsible for several metabolism and biotransformation functions. In this report, we have cultured rat jejunum explants in vitro and integrated them with hepatocyte ... -
An atomic force microscope tip as a light source
(AIP Publishing, 2005-12-01)We present a simple method for causing the end of a silicon nitride atomic force microscope (AFM) tip to emit light, and we use this emitted light to perform scanning near-field optical microscopy. Illumination of a silicon ... -
Bayesian learning of chemisorption for bridging the complexity of electronic descriptors
(Springer Nature, 2020)Building upon the d-band reactivity theory in surface chemistry and catalysis, we develop a Bayesian learning approach to probing chemisorption processes at atomically tailored metal sites. With representative species, ... -
Blood Serum Affects Polysaccharide Production and Surface Protein Expression in S. Aureus
(Juniper Publishers, 2017-01)S. aureus biofilm serves a major role in pathogenesis. Two of the major components of bacterial biofilm are Polysaccharides intercellular adhesions (PIA) and surface proteins. It is not known how PIA and surface proteins ... -
BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells
(2019-04-17)Background BRCA1-associated breast cancer originates from luminal progenitor cells. BRCA1 functions in multiple biological processes, including double-strand break repair, replication stress suppression, transcriptional ... -
Characterizing glucose, illumination, and nitrogen-deprivation phenotypes of Synechocystis PCC6803 with Raman spectroscopy
(2020-03-30)Background. Synechocystis sp. PCC6803 is a model cyanobacterium that has been studied widely and is considered for metabolic engineering applications. Here, Raman spectroscopy and Raman chemometrics (Rametrix (TM)) were ... -
Characterizing metabolic stress-induced phenotypes of Synechocystis PCC6803 with Raman spectroscopy
(2020-03-30)Background. During their long evolution, Synechocystis sp. PCC6803 developed a remarkable capacity to acclimate to diverse environmental conditions. In this study, Raman spectroscopy and Raman chemometrics tools (Rametrix ... -
Comparison Of Flow Birefringence Data with A Numerical-Simulation Of The Hole Pressure
(AIP Publishing, 1988-08-01)The penalty_Galerkin finite_element method is used to simulate the flow of a polystyrene melt over a rectangular slot placed perpendicular to the flow direction. The White_Metzner constitutive equation is used with a Carreau ... -
Comparison Of The Rheological Properties Of Concentrated-Solutions Of A Rodlike And A Flexible Chain Polyamide
(AIP Publishing, 1979)The steady state shear rheological properties of solutions of a rodlike polyamide, poly_p_phenyleneterephthalamide (PPT), in 100% sulfuric acid have been compared with those of solutions of a flexible chain polyamide, nylon ... -
Complex receptor-ligand dynamics control the response of the VEGF system to protease injury
(2011-10-21)Background Vascular homeostasis and response to injury are dependent on the coordinated activity of growth factors such as vascular endothelial growth factor-A (VEGF). VEGF signaling is mediated by VEGF receptors 1 (VEGFR1) ... -
Computational models in plant-pathogen interactions: the case of Phytophthora infestans
(2009-11-12)Background Phytophthora infestans is a devastating oomycete pathogen of potato production worldwide. This review explores the use of computational models for studying the molecular interactions between P. infestans and ... -
Computational study of HIV gp120 as a target for polyanionic entry inhibitors: Exploiting the V3 loop region
(PLOS, 2018-01-18)Multiple approaches are being utilized to develop therapeutics to treat HIV infection. One approach is designed to inhibit entry of HIV into host cells, with a target being the viral envelope glycoprotein, gp120. Polyanionic ... -
Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach
(2019-03-01)Continuous flow chemistry has the potential to greatly improve efficiency in the synthesis of active pharmaceutical ingredients (APIs); however, the optimization of these processes can be complicated by a large number of ... -
A correlation force spectrometer for single molecule measurements under tensile load
(American Institute of Physics, 2013-01-07)The dynamical-mechanical properties of a small region of fluid can be measured using two closely spaced thermally stimulated micrometer-scale cantilevers. We call this technique correlation force spectroscopy (CFS). We ... -
Correlations between the thermal vibrations of two cantilevers: Validation of deterministic analysis via the fluctuation-dissipation theorem
(AIP Publishing, 2012-02-01)We validate a theoretical approach for analyzing correlations in the fluctuations of two cantilevers in terms of a deterministic model, using the fluctuation-dissipation theorem [M. R. Paul and M. C. Cross, Phys. Rev. Lett. ... -
Creation of a gradient polymer-fullerene interface in photovoltaic devices by thermally controlled interdiffusion
(AIP Publishing, 2002-12-01)Efficient polymer-fullerene photovoltaic devices require close proximity of the two materials to ensure photoexcited electron transfer from the semiconducting polymer to the fullerene acceptor. We describe studies in which ...
