Browsing Scholarly Works, Department of Chemical Engineering by Title
Now showing items 1-20 of 91
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3D Hepatic Cultures Simultaneously Maintain Primary Hepatocyte and Liver Sinusoidal Endothelial Cell Phenotypes
(PLOS, 2010-11-12)Developing in vitro engineered hepatic tissues that exhibit stable phenotype is a major challenge in the field of hepatic tissue engineering. However, the rapid dedifferentiation of hepatic parenchymal (hepatocytes) and ... -
Ambient ammonia synthesis via palladium-catalyzed electrohydrogenation of dinitrogen at low overpotential
(Springer Nature, 2018-05-15)Electrochemical reduction of N2 to NH3 provides an alternative to the Haber−Bosch process for sustainable, distributed production of NH3 when powered by renewable electricity. However, the development of such process has ... -
Ammonium Bisphosphonate Polymeric Magnetic Nanocomplexes for Platinum Anticancer Drug Delivery and Imaging with Potential Hyperthermia and Temperature-Dependent Drug Release
(Hindawi, 2018-08-05)Novel magnetite-ammonium bisphosphonate graft ionic copolymer nanocomplexes (MGICs) have been developed for potential drug delivery, magnetic resonance imaging, and hyperthermia applications. The complexes displayed ... -
The assembly of integrated rat intestinal-hepatocyte cultures
(2019-11)The jejunum is the segment of the small intestine responsible for several metabolism and biotransformation functions. In this report, we have cultured rat jejunum explants in vitro and integrated them with hepatocyte ... -
An atomic force microscope tip as a light source
(AIP Publishing, 2005-12-01)We present a simple method for causing the end of a silicon nitride atomic force microscope (AFM) tip to emit light, and we use this emitted light to perform scanning near-field optical microscopy. Illumination of a silicon ... -
BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells
(2019-04-17)Abstract Background BRCA1-associated breast cancer originates from luminal progenitor cells. BRCA1 functions in multiple biological processes, including double-strand break ... -
Comparison Of Flow Birefringence Data with A Numerical-Simulation Of The Hole Pressure
(AIP Publishing, 1988-08-01)The penalty_Galerkin finite_element method is used to simulate the flow of a polystyrene melt over a rectangular slot placed perpendicular to the flow direction. The White_Metzner constitutive equation is used with a Carreau ... -
Comparison Of The Rheological Properties Of Concentrated-Solutions Of A Rodlike And A Flexible Chain Polyamide
(AIP Publishing, 1979)The steady state shear rheological properties of solutions of a rodlike polyamide, poly_p_phenyleneterephthalamide (PPT), in 100% sulfuric acid have been compared with those of solutions of a flexible chain polyamide, nylon ... -
Complex receptor-ligand dynamics control the response of the VEGF system to protease injury
(2011-10-21)Background Vascular homeostasis and response to injury are dependent on the coordinated activity of growth factors such as vascular endothelial growth factor-A (VEGF). VEGF signaling is mediated by VEGF receptors 1 (VEGFR1) ... -
Computational models in plant-pathogen interactions: the case of Phytophthora infestans
(2009-11-12)Background Phytophthora infestans is a devastating oomycete pathogen of potato production worldwide. This review explores the use of computational models for studying the molecular interactions between P. infestans and ... -
Computational study of HIV gp120 as a target for polyanionic entry inhibitors: Exploiting the V3 loop region
(PLOS, 2018-01-18)Multiple approaches are being utilized to develop therapeutics to treat HIV infection. One approach is designed to inhibit entry of HIV into host cells, with a target being the viral envelope glycoprotein, gp120. Polyanionic ... -
Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach
(2019-03-01)Continuous flow chemistry has the potential to greatly improve efficiency in the synthesis of active pharmaceutical ingredients (APIs); however, the optimization of these processes can be complicated by a large number of ... -
A correlation force spectrometer for single molecule measurements under tensile load
(American Institute of Physics, 2013-01-07)The dynamical-mechanical properties of a small region of fluid can be measured using two closely spaced thermally stimulated micrometer-scale cantilevers. We call this technique correlation force spectroscopy (CFS). We ... -
Correlations between the thermal vibrations of two cantilevers: Validation of deterministic analysis via the fluctuation-dissipation theorem
(AIP Publishing, 2012-02-01)We validate a theoretical approach for analyzing correlations in the fluctuations of two cantilevers in terms of a deterministic model, using the fluctuation-dissipation theorem [M. R. Paul and M. C. Cross, Phys. Rev. Lett. ... -
Creation of a gradient polymer-fullerene interface in photovoltaic devices by thermally controlled interdiffusion
(AIP Publishing, 2002-12-01)Efficient polymer-fullerene photovoltaic devices require close proximity of the two materials to ensure photoexcited electron transfer from the semiconducting polymer to the fullerene acceptor. We describe studies in which ... -
Design Of A High-Temperature And High-Pressure Liquid Flow Cell For X-Ray Absorption Fine Structure Measurements Under Catalytic Reaction Conditions
(AIP Publishing, 2008-01-01)The design and performance of a new high-pressure and high-temperature cell for measurement of x-ray absorption fine structure (XAFS) spectra of solid catalysts working in a flowing liquid are presented. The cell has flat, ... -
Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures
(PLOS, 2011-01-05)The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs and environmental ... -
Dynamic contact angle of water-based titanium oxide nanofluid
(2013-06-11)This paper presents an investigation into spreading dynamics and dynamic contact angle of TiO2-deionized water nanofluids. Two mechanisms of energy dissipation, (1) contact line friction and (2) wedge film viscosity, govern ... -
Dynamic Mechanical And Thermal Behavior Of Novel Liquid-Crystalline Polybutadiene-Diols with Azobenzene Groups in Side Chains
(AIP Publishing, 2013-09-01)Liquid-crystalline (LC) polymers containing methoxy-or butoxy-substituted azobenzene in side chains have been prepared via radical addition of the in advance synthesized nematic thiols onto double bonds of poly(butadiene) ... -
Effects of receptor clustering on ligand dissociation kinetics: Theory and simulations
(CELL PRESS, 2005-12-01)Receptor-ligand binding is a critical first step in signal transduction and the duration of the interaction can impact signal generation. In mammalian cells, clustering of receptors may be facilitated by heterogeneous zones ...
