Browsing Scholarly Works, Department of Biochemistry by Title
Now showing items 1-20 of 262
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3,4-Dihydroxyphenylacetaldehyde synthase and cuticle formation in insects
(2018-06-02)Cuticle is the most important structure that protects mosquitoes and other insect species from adverse environmental conditions and infections of microorganism. The physiology and biochemistry of insect cuticle formation ... -
Activation of PAD4 in NET formation.
(2012)Peptidylarginine deiminases, or PADs, convert arginine residues to the non-ribosomally encoded amino acid citrulline in a variety of protein substrates. PAD4 is expressed in granulocytes and is essential for the formation ... -
Activation of SsoPK4, an Archaeal eIF2α Kinase Homolog, by Oxidized CoA
(MDPI, 2015-05-15)The eukaryotic protein kinase (ePK) paradigm provides integral components for signal transduction cascades throughout nature. However, while so-called typical ePKs permeate the Eucarya and Bacteria, ... -
Analysis of T-DNA alleles of flavonoid biosynthesis genes in Arabidopsis ecotype Columbia
(2012-09-04)BACKGROUND: The flavonoid pathway is a long-standing and important tool for plant genetics, biochemistry, and molecular biology. Numerous flavonoid mutants have been identified in Arabidopsis over the past several decades ... -
Analysis of the Aedes albopictus C6/36 genome provides insight into cell line utility for viral propagation
(2018-03)The 50-year old Aedes albopictus C6/36 cell line is a resource for the detection, amplification, and analysis of mosquito-borne viruses including Zika, dengue, and chikungunya. The cell line is derived from an unknown ... -
AnfO controls fidelity of nitrogenase FeFe protein maturation by preventing misincorporation of FeV-cofactor
(Wiley, 2022-05)Azotobacter vinelandii produces three genetically distinct, but structurally and mechanistically similar nitrogenase isozymes designated as Mo-dependent, V-dependent, or Fe-only based on the heterometal contained within ... -
Anopheles mosquitoes reveal new principles of 3D genome organization in insects
(Nature Portfolio, 2022-04-12)Chromosomes are hierarchically folded within cell nuclei into territories, domains and subdomains, but the functional importance and evolutionary dynamics of these hierarchies are poorly defined. Here, we comprehensively ... -
Antimalarial 5,6-Dihydro-alpha-pyrones from Cryptocarya rigidifolia: Related Bicyclic Tetrahydro-alpha-Pyrones Are Artifacts
(Amer Chemical Soc, 2015-06-01) -
Antiproliferative Compounds from Cleistanthus boivinianus from the Madagascar Dry Forest
(Amer Chemical Soc, 2015-07-01) -
AvrRxo1 Is a Bifunctional Type III Secreted Effector and Toxin-Antitoxin System Component with Homologs in Diverse Environmental Contexts
(PLOS, 2016-07-08)Toxin-antitoxin (TA) systems are ubiquitous bacterial systems that may function in genome maintenance and metabolic stress management, but are also thought to play a role in virulence by helping pathogens survive stress. ... -
The Beginning of the End: A Chromosomal Assembly of the New World Malaria Mosquito Ends with a Novel Telomere
(Genetics Society of America, 2020-10-01)Chromosome level assemblies are accumulating in various taxonomic groups including mosquitoes. However, even in the few reference-quality mosquito assemblies, a significant portion of the heterochromatic regions including ... -
Biochemical Characterization of a Dihydroneopterin Aldolase Used for Methanopterin Biosynthesis in Methanogens
(American Society for Microbiology, 2014-06-30)The gene encoding 7,8-dihydroneopterin aldolase (DHNA) was recently identified in archaea through comparative genomics as being involved in methanopterin biosynthesis (V. Crecy-Lagard, G. Phillips, L. L. Grochowski, B. El ... -
Biogenic formation of amorphous carbon by anaerobic methanotrophs and select methanogens
(AAAS, 2021-10-27)Elemental carbon exists in different structural forms including graphite, diamond, fullerenes, and amorphous carbon. In nature, these materials are produced through abiotic chemical processes under high temperature and ... -
Biosynthesis and possible functions of inositol pyrophosphates in plants
(Frontiers Research Foundation, 2015-02-12)Inositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. ... -
Biosynthesis of Galactofuranose in Kinetoplastids: Novel Therapeutic Targets for Treating Leishmaniasis and Chagas' Disease
(Hindawi, 2011-05-25)Cell surface proteins of parasites play a role in pathogenesis by modulating mammalian cell recognition and cell adhesion during infection. β-Galactofuranose (Galf) is an important component of glycoproteins and glycolipids ... -
Biosynthesis of the nitrogenase active-site cofactor precursor NifB-co in Saccharomyces cerevisiae
(National Academy of Sciences, 2019-12-10)The radical S-adenosylmethionine (SAM) enzyme NifB occupies a central and essential position in nitrogenase biogenesis. NifB catalyzes the formation of an [8Fe-9S-C] cluster, called NifB-co, which constitutes the core of ... -
Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis
(National Academy of Sciences, 2019-06-17)Lyme disease is a multisystem disorder caused by the spirochete Borrelia burgdorferi. A common late-stage complication of this disease is oligoarticular arthritis, often involving the knee. In ∼10% of cases, arthritis ... -
Borrelia burgdorferi SpoVG DNA- and RNA-Binding Protein Modulates the Physiology of the Lyme Disease Spirochete
(AMER SOC MICROBIOLOGY, 2018-06-01)
