Browsing Scholarly Works, Department of Biological Systems Engineering by Title
Now showing items 1-20 of 278
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13C-Metabolic Flux Analysis: An Accurate Approach to Demystify Microbial Metabolism for Biochemical Production
(MDPI, 2015-12-25)Metabolic engineering of various industrial microorganisms to produce chemicals, fuels, and drugs has raised interest since it is environmentally friendly, sustainable, and independent of nonrenewable resources. However, ... -
A protein therapeutic modality founded on molecular regulation.
(2011-09-19)The exquisite specificity of proteins is a key feature driving their application to anticancer therapies. The therapeutic potential of another fundamental property of proteins, their ability to be regulated by molecular ... -
Accelerating structure-function mapping using the ViVa webtool to mine natural variation
Thousands of sequenced genomes are now publicly available capturing a significant amount of natural variation within plant species; yet, much of this data remains inaccessible to researchers without significant bioinformatics ... -
Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy.
(2014-01)While gene-directed enzyme prodrug therapy has shown potential as a cancer therapeutic in animal and clinical trials, concerns over the efficacy, selectivity, and safety of gene delivery vehicles have restricted its advance. ... -
Advances in Biochemical Engineering-Biotechnology
(Springer, 2014-07-15)In vitro hydrogen generation represents a clear opportunity for novel bioreactor and system design. Hydrogen, already a globally important commodity chemical, has the potential to become the dominant transportation fuel ... -
Advances in Watershed Management: Modeling, Monitoring, and Assessment
(American Society of Agricultural and Biological Engineers, 2011)This article introduces a special collection of nine articles that address a wide range of topics all related to improving the application of watershed management planning. The articles are grouped into two broadly defined ... -
Application of a New Species-Richness Based Flow Ecology Framework for Assessing Flow Reduction Effects on Aquatic Communities
(2020)Water-resources managers are challenged with maintaining a balance among beneficial uses throughout river networks and need robust means of assessing potential risks to aquatic life resulting from flow alterations. This ... -
Armored kinorhynch-like scalidophoran animals from the early Cambrian.
(2015-11-26)Morphology-based phylogenetic analyses support the monophyly of the Scalidophora (Kinorhyncha, Loricifera, Priapulida) and Nematoida (Nematoda, Nematomorpha), together constituting the monophyletic Cycloneuralia that is ... -
Assembly of Bio-Nanoparticles for Double Controlled Drug Release
(PLOS, 2013-09-06)A critical limiting factor of chemotherapy is the unacceptably high toxicity. The use of nanoparticle based drug carriers has significantly reduced the side effects and facilitated the delivery of drugs. Source of the ... -
Assessing Strontium and Vulnerability to Strontium in Private Drinking Water Systems in Virginia
(MDPI, 2020-04-08)A total of 1.7 million Virginians rely on private drinking water (PDW) systems and 1.3 million of those people do not know their water quality. Because most Virginians who use PDW do not know the quality of that water and ... -
Assessing the Effects of Climate Change on Water Quantity and Quality in an Urban Watershed Using a Calibrated Stormwater Model
(MDPI, 2017-06-27)Assessing climate change (CC) impacts on urban watersheds is difficult due to differences in model spatial and temporal scales, making prediction of hydrologic restoration a challenge. A methodology was developed using an ... -
Assessment and validation of total water storage in the Chesapeake Bay watershed using GRACE
(Elsevier, 2019-05-22)The Chesapeake Bay is the largest estuary in the United States, and its catchment has heterogeneous hydrological and geomorphologic characteristics. It includes seven major river basins: James, Patuxent, Potomac, Rappahannock, ... -
Assistive Technologies in Agriculture
(Virginia Cooperative Extension, 2010-07-01)Assistive technology can help farmers and ranchers who have disabilities or primary injuries to continue to be productive while reducing secondary injuries. -
Automatic Calibration Tool for Hydrologic Simulation Program-FORTRAN Using a Shuffled Complex Evolution Algorithm
(MDPI, 2015-02-04)Hydrologic Simulation Program-Fortran (HSPF) model calibration is typically done manually due to the lack of an automated calibration tool as well as the difficulty of balancing objective functions to be considered. This ... -
A Bayesian Assignment Method for Ambiguous Bisulfite Short Reads
(PLOS, 2016-03-24)DNA methylation is an epigenetic modification critical for normal development and diseases. The determination of genome-wide DNA methylation at single-nucleotide resolution is made possible by sequencing bisulfite treated ... -
Biochemical properties of GH94 cellodextrin phosphorylase THA_1941 from a thermophilic eubacterium Thermosipho africanus TCF52B with cellobiose phosphorylase activity
(Springer Nature, 2017-07-07)A hypothetic gene (THA_1941) encoding a putative cellobiose phosphorylase (CBP) from Thermosipho africanus TCF52B has very low amino acid identities (less than 12%) to all known GH94 enzymes. This gene was cloned and ... -
Biodiesel Fuel
(Virginia Cooperative Extension, 2015-01-14)Introduces the basics of biodiesel fuel, addresses some consumer myths, and answers questions about biodiesel fuel before farmers and fleet owners begin to use it.
