Now showing items 1-4 of 4
Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells
Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the ...
Identifying Transcriptional Regulatory Modules Among Different Chromatin States in Mouse Neural Stem Cells
Gene expression regulation is a complex process involving the interplay between transcription factors and chromatin states. Significant progress has been made toward understanding the impact of chromatin states on gene ...
Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury
(Springer Nature, 2019-06-12)
The peripheral immune system is a major regulator of the pathophysiology associated with traumatic brain injury (TBI). While age-at-injury influences recovery from TBI, the differential effects on the peripheral immune ...
Virtual methylome dissection facilitated by single-cell analyses
Abstract Background Numerous cell types can be identified within plant tissues and animal organs, and the epigenetic modifications underlying such enormous cellular heterogeneity are just beginning to be understood. It ...