Now showing items 1-3 of 3
vi-HMM: a novel HMM-based method for sequence variant identification in short-read data
Abstract Background Accurate and reliable identification of sequence variants, including single nucleotide polymorphisms (SNPs) and insertion-deletion polymorphisms (INDELs), ...
Identifying Transcriptional Regulatory Modules Among Different Chromatin States in Mouse Neural Stem Cells
Gene expression regulation is a complex process involving the interplay between transcription factors and chromatin states. Significant progress has been made toward understanding the impact of chromatin states on gene ...
A Bayesian Analysis of Copy Number Variations in Array Comparative Genomic Hybridization Data
(OMICS International, 2015-09-25)
Array Comparative Genomic Hybridization (CGH) has been widely used for detecting genomic copy number variations (CNVs). The central goal of array CGH data analysis is to accurately detect homogeneous regions of log intensity ...