Browsing Faculty Works, Department of Biomedical Sciences and Pathobiology by Issue Date

Examination of extraintestinal tissue cysts of Isospora belli

Lindsay, D. S.; Dubey, J. P.; ToivioKinnucan, M. A.; Michiels, J. F.; Blagburn, B. L. (American Society of Parasitology, 1997-08)

Relapse is common in immunocompetent and immunosuppressed humans infected with Isospora belli and is believed to be associated with the presence of extraintestinal stages. In the present study, we examined this important ...

Vaccination of mice with Neospora caninum: Response to oral challenge with Toxoplasma gondii oocysts

Lindsay, D. S.; Lenz, S. D.; Dykstra, C. C.; Blagburn, B. L.; Dubey, J. P. (American Society of Parasitology, 1998-04)

Neospora caninum is a protozoan parasite that can cause severe disease in mammals. Two experiments were conducted to examine the effects of subcutaneous (s.c.) vaccination with Hank's balanced salt solution (HBSS), 1 x ...

Complete development of the porcine coccidium Isospora suis Biester, 1934 in cell cultures

Lindsay, D. S.; Quick, D. P.; Steger, A. M.; Toivio-Kinnucan, M. A.; Blagburn, B. L. (American Society of Parasitology, 1998-06)

Development from inoculated sporozoites to unsporulated oocysts of Isospora suis Biester, 1934 is described in a swine testicular (ST) cell line. Sporozoites penetrated ST cells within 1 hr postinoculation (PI). Development ...

Characterization of temperature-sensitive strains of Neospora caninum in mice

Lindsay, D. S.; Lenz, S. D.; Blagburn, B. L.; Brake, D. A. (American Society of Parasitology, 1999-02)

Temperature-sensitive (ts) strains of the Neospora caninum tachyzoites were selected by chemical mutagenesis and selection for growth at 32 C. Three ts strains and the parental, N. caninum wild-type strain, NC-1, were ...

Development of Sarcocystis falcatula in cell cultures demonstrates that it is different from Sarcocystis neurona

Lindsay, D. S.; Dubey, J. P.; Horton, K. M.; Bowman, D. D. (Cambridge University Press, 1999-03)

The development of Sarcocystis falcatula merozoites in bovine turbinate (BT) cell cultures is described and compared with development of Sarcocystis neurona merozoites. Merozoites of S. falcatula entered BT cell cultures ...

Descriptions of two new species of coccidia (Protozoa : Eimeriidae) and redescriptions of Eimeria ivensae and Eimeria odocoilei from captive white-tailed deer, Odocoileus virginianus

Lindsay, D. S.; Upton, S. J.; Hildreth, M. B. (American Society of Parasitology, 1999-12)

Two new species of Eimeria were observed in the feces of captive white-tailed deer fawns, Odocoileus virginianus, from Alabama. The first new species was easily recognized because of its small size. Sporulated oocysts are ...

Determination of the activity of diclazuril against Sarcocystis neurona and Sarcocystis falcatula in cell cultures

Lindsay, D. S.; Dubey, J. P. (American Society of Parasitology, 2000-02)

Diclazuril is a benzeneacetonitril anticoccidial that has excellent activity against the extraintestinal stages of Toxoplasma gondii and Neospora caninum. It also is highly active against intestinal coccidia of poultry. ...

Sarcocystis campestris from naturally infected 13-lined ground squirrels, Spermophilus tridecemlineatus tridecemlineatus, from Nebraska

Lindsay, D. S.; McKown, R. D.; Dubey, J. P. (American Society of Parasitology, 2000-10)

Grossly visible sarcocysts were seen in the skeletal muscles of 1 of 12 13-lined ground squirrels, Spermophilus tridecemlineatus tridecemlineatus, collected in Nebraska. The tissue cyst wall was up to 5.0 mum thick and ...

The South American opossum, Didelphis marsupialis, from Brazil as another definitive host for Sarcocystis speeri Dubey and Lindsay, 1999

Dubey, J. P.; Kerber, C. E.; Lindsay, D. S.; Kasai, N.; Pena, H. F. J. (Cambridge University Press, 2000-12)

The North American opossum, Didelphis virginiana, is a definitive host for at least 3 species of Sarcocystis: S. falcatula Stiles 1983, S. neurona Dubey, Davis, Speer, Bowman, de Lahunta, Granstrom, Topper, Hamir, Cummings, ...

Oocyst excretion in dogs fed mouse brains containing tissue cysts of a cloned line of Neospora caninum

Lindsay, D. S.; Ritter, D. M.; Brake, D. (American Society of Parasitology, 2001-08)

Neospora caninum is an apicomplexan parasite that causes neonatal neuromuscular disease in dogs and abortions in cattle. Bovine neosporosis is a major production problem worldwide. The parasite is transmitted to cattle via ...

Prevalence of agglutinating antibodies to Neospora caninum in raccoons, Procyon lotor

Lindsay, D. S.; Spencer, J.; Rupprecht, C.; Blagburn, B. L. (American Society of Parasitology, 2001-10)

Neospora caninum is an apicomplexan parasite that causes neonatal neuromuscular disease in dogs and abortions in cattle. Dogs are the only proven definitive host. Little is known about the prevalence of antibodies to this ...

The gamma interferon knockout mouse model for Sarcocystis neurona: Comparison of infectivity of sporocysts and merozoites and routes of inoculation

Dubey, J. P.; Lindsay, D. S.; Kwok, O. C. H.; Shen, S. K. (American Society of Parasitology, 2001-10)

The dose-related infectivity of Sarcocystis neurona sporocysts and merozoites. of 2 recent isolates of S. neurona was compared in gamma interferon knockout (KO) mice. Tenfold dilutions of sporocysts or merozoites were ...

Use of molecular probes to assess geographic distribution of Pfiesteria species

Rublee, Parke A.; Kempton, Jason W.; Schaefer, Eric F.; Allen, Coy; Harris, Janera; Oldach, David W.; Bowers, Holly; Tengs, Torstein; Burkholder, JoAnn M.; Glasgow, H. B. (US Department of Health and Human Sciences, Public Health Science, 2001-10-01)

We have developed multiple polymerase chain reaction (PCR)-based methods for the detection of Pfiesteria sp. in cultures and environmental samples. More than 2,100 water and sediment samples from estuarine sites of the ...

Isolates of Sarcocystis falcatula-like organisms from South American opossums Didelphis marsupialis and Didelphis albiventris from Sao Paulo, Brazil

Dubey, J. P.; Lindsay, D. S.; Rosenthal, B. M.; Kerber, C. E.; Kasai, N.; Pena, H. F. J.; Kwok, O. C. H.; Shen, S. K.; Gennari, S. M. (American Society of Parasitology, 2001-12)

Isolates of Sarcocystis falcatula-like organisms from South American opossums were characterized based on biological and morphological criteria. Sporocysts from intestinal scrapings of 1 Didelphis marsupialis and 8 Didelphis ...

Sarcocystis neurona infections in sea otter (Enhydra lutris): Evidence for natural infections with sarcocysts and transmission of infection to opossums (Didelphis virginiana)

Dubey, J. P.; Rosypal, A. C.; Rosenthal, B. M.; Thomas, N. J.; Lindsay, D. S.; Stanek, J. F.; Reed, S. M.; Saville, W. J. A. (American Society of Parasitology, 2001-12)

Although Sarcocystis neurona has been identified in an array of terrestrial vertebrates, recent recognition of its capacity to infect marine mammals was unexpected. Here, sarcocysts from 2 naturally infected sea otters ...

Prevalence of antibodies to Neospora caninum in white-tailed deer, Odocoileus virginianus, from the southeastern United States

Lindsay, D. S.; Little, S. E.; Davidson, W. R. (American Society of Parasitology, 2002-04)

Serum samples from 305 white-tailed deer (Odocoileus virginianus) from 14 states in the southeastern United States were examined for antibodies to Neospora caninum using a direct agglutination test. Positive a,agglutination ...

Prevalence of agglutinating antibodies to Sarcocystis neurona in skunks (Mephitis mephitis), raccoons (Procyon lotor), and opossums (Didelphis virginiana) from Connecticut

Mitchell, S. M.; Richardson, D. J.; Cheadle, M. A.; Zajac, A. M.; Lindsay, D. S. (American Society of Parasitology, 2002-10)

Equine protozoal myeloencephalitis is the most important protozoan disc a 6 of horses in North America and is usually caused by Sarcocystis neuronal Natural cases of encephalitis caused by S. neurona have been reported in ...