Browsing Faculty Works, Department of Biomedical Sciences and Pathobiology by Title
Now showing items 1-20 of 106
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A Review: competence, compromise, and concomitance-reaction of the host cell to toxoplasma gondii infection and development
(American Society of Parasitology, 2011-08)Toxoplasma gondii is an important zoonotic parasite with a worldwide distribution. It infects about one-third of the world's population, causing serious illness in immunosuppressed individuals, fetuses, and infants. ... -
Besnoitia oryctofelisi n. sp (Protozoa : Apicomplexa) from domestic rabbits
(Cambridge University Press, 2003-06)A species of Besnoitia from naturally infected rabbits from Argentina was propagated experimentally in mice, gerbils, rabbits, cats, and cell cultures. Cats fed tissue cysts from rabbits shed oocysts with a prepatent period ... -
Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
(PLOS, 2016-08-08)We investigated Brucella melitensis methionyl-tRNA-synthetase (BmMetRS) with molecular, structural and phenotypic methods to learn if BmMetRS is a promising target for brucellosis drug development. Recombinant BmMetRS was ... -
Canine Cancer Screening Via Ultraviolet Absorbance And Fluorescence Spectroscopy Of Serum Proteins
(Optical Society of America, 2007-01-01)A cost-effective optical cancer screening and monitoring technique was demonstrated in a pilot study of canine serum samples and was patented for commercialization. Compared to conventional blood chemistry analysis methods, ... -
Characterization of temperature-sensitive strains of Neospora caninum in mice
(American Society of Parasitology, 1999-02)Temperature-sensitive (ts) strains of the Neospora caninum tachyzoites were selected by chemical mutagenesis and selection for growth at 32 C. Three ts strains and the parental, N. caninum wild-type strain, NC-1, were ... -
Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound
(2011-05-31)Background Accidental autoclaving of L-glutamine was found to facilitate the Agrobacterium infection of a non host plant like tea in an earlier study. In the present communication, we elucidate the structural changes in ... -
Comparable growth of Tritrichomonas mobilensis in two commercially available culture media
(American Society of Parasitology, 2002-10)The investigation reported herein was undertaken to determine which medium is more practical for the axenic laboratory culture of trichomonads. The growth of Tritrichomonas mobilensis was monitored in 2 different types of ... -
Comparison of Commercial Real-Time Reverse Transcription-PCR Assays for Reliable, Early, and Rapid Detection of Heterologous Strains of Porcine Reproductive and Respiratory Syndrome Virus in Experimentally Infected or Noninfected Boars by Use of Different Sample Types
(American Society for Microbiology, 2012-12-05)The aims of this study were to compare three commercial porcine reproductive and respiratory syndrome virus (PRRSV) real-time reverse transcription-PCR (RT-PCR) assays for detection of genetically diverse PRRSV isolates ... -
Comparison of Real-Time Reverse Transcriptase PCR Assays for Detection of Swine Hepatitis E Virus in Fecal Samples
(American Society for Microbiology, 2014-01-15)Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in people in many developing countries and is also endemic in many industrialized countries. Mammalian HEV (mHEV) isolates can be divided into at least four ... -
Complete development of the porcine coccidium Isospora suis Biester, 1934 in cell cultures
(American Society of Parasitology, 1998-06)Development from inoculated sporozoites to unsporulated oocysts of Isospora suis Biester, 1934 is described in a swine testicular (ST) cell line. Sporozoites penetrated ST cells within 1 hr postinoculation (PI). Development ... -
Complexity, fractals, disease time, and cancer
(American Physical Society, 2004-12)Despite many years of research, a method to precisely and quantitatively determine cancer disease state remains elusive. Current practice for characterizing solid tumors involves the use of varying systems of tumor grading ... -
Congenital infection of mice with toxoplasma gondii induces minimal change in behavior and no change in neurotransmitter concentrations
(American Society of Parasitology, 2012-08-01)We examined the effect of maternal Toxoplasma gondii infection on behavior and the neurotransmitter concentrations of congenitally infected CD-I mice at 4 and 8 wk of age when latent tissue cysts would be present in their ... -
Coordinated Zinc Homeostasis Is Essential for the Wild-Type Virulence of Brucella abortus
(American Society for Microbiology, 2015-02-17)Metal homeostasis in bacterial cells is a highly regulated process requiring intricately coordinated import and export, as well as precise sensing of intracellular metal concentrations. The uptake of zinc (Zn) has been ... -
Cystoisospora canis Nemeseri, 1959 (Syn. Isospora canis), infections in dogs: Clinical signs, pathogenesis, and reproducible clinical disease in beagle dogs fed oocysts
(American Society of Parasitology, 2007-04)Canine intestinal coccidiosis is a cause of diarrhea in young dogs and dogs that are immunocompromised. Reports in the literature indicate that experimental reproduction of clinical coccidiosis with Cystoisospora canis ... -
Dehydroepiandrosterone protects vascular endothelial cells against apoptosis through a G alpha(i) protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression
(Endocrine Society, 2007-07)The adrenal steroid dehydroepiandrosterone (DHEA) may improve vascular function, but the mechanism is unclear. In the present study, we show that DHEA significantly increased cell viability, reduced caspase-3 activity, and ... -
Descriptions of two new species of coccidia (Protozoa : Eimeriidae) and redescriptions of Eimeria ivensae and Eimeria odocoilei from captive white-tailed deer, Odocoileus virginianus
(American Society of Parasitology, 1999-12)Two new species of Eimeria were observed in the feces of captive white-tailed deer fawns, Odocoileus virginianus, from Alabama. The first new species was easily recognized because of its small size. Sporulated oocysts are ... -
Detection of Hammondia heydorni-like organisms and their differentiation from Neospora caninum using random-amplified polymorphic DNA-polymerase chain reaction
(American Society of Parasitology, 2003-10)Neospora caninum and Hammondia heydorni are morphologically and phylogenetically related coccidians that are found in dogs. New diagnostic genetic loci, based on random-amplified polymorphic DNA-polymerase chain reaction ... -
Determination of the activity of diclazuril against Sarcocystis neurona and Sarcocystis falcatula in cell cultures
(American Society of Parasitology, 2000-02)Diclazuril is a benzeneacetonitril anticoccidial that has excellent activity against the extraintestinal stages of Toxoplasma gondii and Neospora caninum. It also is highly active against intestinal coccidia of poultry. ... -
Development and ultrastructure of cystoisospora canis nemeseri, 1959 (syn. isospora canis) monozoic cysts in two noncanine cell lines
(American Society of Parasitology, 2009-08)Cystoisospora canis is a coccidial parasite of the intestinal tract that can cause severe disease in dogs. Clinical Signs include watery diarrhea, vomiting, fever, and weight loss. Extraintestinal stages of Cystoisospora ... -
Development and validation of a negative-strand-specific reverse transcription-PCR assay for detection of a chicken strain of hepatitis E virus: Identification of nonliver replication sites
(American Society for Microbiology, 2008-06-18)As a positive-strand RNA virus, hepatitis E virus ( HEV) produces an intermediate negative-strand RNA when it replicates. Thus, the detection of negative-strand viral RNA is indicative of HEV replication. The objective of ...
