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    • Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial 

      Boswood, A.; Haggstrom, J.; Gordon, S. G.; Wess, G.; Stepien, R. L.; Oyama, M. A.; Keene, B. W.; Bonagura, J.; MacDonald, K. A.; Patteson, M.; Smith, S.; Fox, P. R.; Sanderson, K.; Woolley, R.; Szatmari, V.; Menaut, P.; Church, W. M.; O'Sullivan, M. L.; Jaudon, J-P; Kresken, J-G; Rush, J.; Barrett, K. A.; Rosenthal, S. L.; Saunders, A. B.; Ljungvall, I.; Deinert, M.; Bomassi, E.; Estrada, A. H.; Fernandez Del Palacio, M. J.; Moise, N. S.; Abbott, J. A.; Fujii, Y.; Spier, A.; Luethy, M. W.; Santilli, R. A.; Uechi, M.; Tidholm, A.; Watson, P. (American College of Veterinary Internal Medicine, 2016-11)
      Background: Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on dogs before the onset of CHF is unknown. Hypothesis/Objectives: ...