Now showing items 85-104 of 323

    • Economic and Social Impact of Influenza Mitigation Strategies by Demographic Class 

      Barrett, Christopher L.; Bisset, Keith; Leidig, Jonathan; Marathe, Achla; Marathe, Madhav (Elsevier, 2011-03-01)
      Background—We aim to determine the economic and social impact of typical interventions proposed by the public health officials and preventive behavioral changes adopted by the private citizens in the event of a “flu-like” ...
    • Effect of modelling slum populations on influenza spread in Delhi 

      Chen, J; Chu, S; Chungbaek, Y; Khan, M; Kuhlman, C; Marathe, A; Mortveit, H; Vullikanti, A; Xie, D (Bmj Publishing Group, 2016-01-01)
    • Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutations 

      Rouxel, Thierry; Grandaubert, Jonathan; Hane, James K.; Hoede, Claire; van de Wouw, Angela P.; Couloux, Arnaud; Dominguez, Victoria; Anthouard, Veronique; Bally, Pascal; Bourras, Salim; Cozijnsen, Anton J.; Ciuffetti, Lynda M.; Degrave, Alexandre; Dilmaghani, Azita; Duret, Laurent; Fudal, Isabelle; Goodwin, Stephen B.; Gout, Lilian; Glaser, Nicolas; Linglin, Juliette; Kema, Gert H. J.; Lapalu, Nicolas; Lawrence, Christopher B.; May, Kim; Meyer, Michel; Ollivier, Benedicte; Poulain, Julie; Schoch, Conrad L.; Simon, Adeline; Spatafora, Joseph W.; Stachowiak, Anna; Turgeon, B. Gillian; Tyler, Brett M.; Vincent, Delphine; Weissenbach, Jean; Amselem, Joelle; Quesneville, Hadi; Oliver, Richard P.; Wincker, Patrick; Balesdent, Marie-Helene; Howlett, Barbara J. (Springer Nature, 2011-02)
      Fungi are of primary ecological, biotechnological and economic importance. Many fundamental biological processes that are shared by animals and fungi are studied in fungi due to their experimental tractability. Many fungi ...
    • An emerging cyberinfrastructure for biodefense pathogen and pathogen-host data 

      Zhang, C.; Crasta, O.; Cammer, S.; Will, R.; Kenyon, R.; Sullivan, D.; Yu, Q.; Sun, W.; Jha, R.; Liu, D.; Xue, T.; Zhang, Y.; Moore, M.; McGarvey, P.; Huang, H.; Chen, Y.; Zhang, J.; Mazumder, R.; Wu, C.; Sobral, B. (2008-01)
      The NIAID-funded Biodefense Proteomics Resource Center (RC) provides storage, dissemination, visualization and analysis capabilities for the experimental data deposited by seven Proteomics Research Centers (PRCs). The data ...
    • Empirical study using network of semantically related associations in bridging the knowledge gap 

      Abedi, Vida; Yeasin, Mohammed; Zand, Ramin (2014-11-27)
      Background The data overload has created a new set of challenges in finding meaningful and relevant information with minimal cognitive effort. However designing robust and scalable knowledge discovery systems remains a ...
    • Endocytic Markers Associated with the Internalization and Processing of Aspergillus fumigatus Conidia by BEAS-2B Cells 

      Clark, H.R.; Powell, A.B.; Simmons, K.A.; Ayubi, T.; Kale, S.D. (NLM (Medline), 2019-02-06)
      Aspergillus fumigatus is a ubiquitous mold that produces small airborne conidia capable of traversing deep into the respiratory system. Recognition, processing, and clearance of A. fumigatus conidia by bronchial airway ...
    • Enhancing disease surveillance with novel data streams: challenges and opportunities 

      Althouse, Benjamin M.; Scarpino, Samuel V.; Meyers, Lauren Ancel; Ayers, John W.; Bargsten, Marisa; Baumbach, Joan; Brownstein, John S.; Castro, Lauren; Clapham, Hannah; Cummings, Derek AT; Del Valle, Sara; Eubank, Stephen; Fairchild, Geoffrey; Finelli, Lyn; Generous, Nicholas; George, Dylan; Harper, David R.; Hebert-Dufresne, Laurent; Johansson, Michael A.; Konty, Kevin; Lipsitch, Marc; Millinovich, Gabriel; Miller, Joseph D.; Nsoesie, Elaine O.; Olson, Donald R.; Paul, Michael|Polgreen, Philip M.; Priedhorsky, Reid; Read, Jonathan M.; Rodriguez-Barraquer, Isabel; Smith, Derek J.; Stefansen, Christian; Swerdlow, David L.; Thompson, Deborah; Vespignani, Alessandro; Wesolowski, Amy (Springer, 2015)
      Novel data streams (NDS), such as web search data or social media updates, hold promise for enhancing the capabilities of public health surveillance. In this paper, we outline a conceptual framework for integrating NDS ...
    • An Ensemble Approach to Predicting the Impact of Vaccination on Rotavirus Disease in Niger 

      Park, J; Goldstein, J; Haran, M; Ferrari, M
      Recently developed vaccines provide a new way of controlling rotavirus in sub-Saharan Africa. Models for the transmission dynamics of rotavirus are critical both for estimating current burden from imperfect surveillance ...
    • Enzymatic, immunological and phylogenetic characterization of Brucella suis urease 

      Contreras-Rodriguez, Araceli; Quiroz-Limon, Jose; Martins, Ana M.; Peralta, Humberto; Avila-Calderon, Eric; Sriranganathan, Nammalwar; Boyle, Stephen M.; Lopez-Merino, Ahide (2008-07-19)
      Background The sequenced genomes of the Brucella spp. have two urease operons, ure-1 and ure-2, but there is evidence that only one is responsible for encoding an active urease. The present work describes the purification ...
    • EpiViewer: an epidemiological application for exploring time series data 

      Thorve, Swapna; Wilson, Mandy L.; Lewis, Bryan L.; Swarup, Samarth; Vullikanti, Anil Kumar S.; Marathe, Madhav V. (2018-11-22)
      Abstract Background Visualization plays an important role in epidemic time series analysis and forecasting. Viewing time series data plotted on a graph can help researchers ...
    • Estimating Human Cases of Avian Influenza A(H7N9) from Poultry Exposure 

      Rivers, Caitlin; Lum, Kristian; Lewis, Bryan; Eubank, Stephen (PLOS, 2013-05-15)
      In March 2013 an outbreak of avian influenza A(H7N9) was first recognized in China. To date there have been 130 cases in human, 47% of which are in men over the age of 55.The influenza strain is a novel subtype not seen ...
    • EvoCor: a platform for predicting functionally related genes using phylogenetic and expression profiles 

      Dittmar, W. James; McIver, Lauren; Michalak, Pawel; Garner, Harold R.; Valdez, Gregorio (2014-07-01)
      The wealth of publicly available gene expression and genomic data provides unique opportunities for computational inference to discover groups of genes that function to control specific cellular processes. Such genes are ...
    • Exome-Wide Somatic Microsatellite Variation Is Altered in Cells with DNA Repair Deficiencies 

      Vaksman, Zalman; Fonville, Natalie C.; Tae, Hongseok; Garner, Harold R. (PLOS, 2014-11-17)
      Microsatellites (MST), tandem repeats of 1–6 nucleotide motifs, are mutational hot-spots with a bias for insertions and deletions (INDELs) rather than single nucleotide polymorphisms (SNPs). The majority of MST instability ...
    • Experimental testing of a new integrated model of the budding yeast Start transition 

      Adames, N. R.; Schuck, P. L.; Chen, K. C.; Murali, T. M.; Tyson, John J.; Peccoud, J. (Amer Soc Cell Biology, 2015-11-05)
    • Feature selection of gene expression data for Cancer classification using double RBF-kernels 

      Liu, Shenghui; Xu, Chunrui; Zhang, Yusen; Liu, Jiaguo; Yu, Bin; Liu, Xiaoping; Dehmer, Matthias (2018-10-29)
      Abstract Background Using knowledge-based interpretation to analyze omics data can not only obtain essential information regarding various biological processes, but also reflect ...
    • Feedback Between Behavioral Adaptations and Disease Dynamics 

      Chen, Jiangzhuo; Marathe, Achla; Marathe, Madhav (Springer Nature, 2018-08-20)
      We study the feedback processes between individual behavior, disease prevalence, interventions and social networks during an influenza pandemic when a limited stockpile of antivirals is shared between the private and the ...
    • Forecasting Social Unrest Using Activity Cascades 

      Cadena, Jose; Korkmaz, Gizem; Kuhlman, Chris J.; Marathe, Achla; Ramakrishnan, Naren; Vullikanti, Anil (PLOS, 2015-06-19)
      Social unrest is endemic in many societies, and recent news has drawn attention to happenings in Latin America, the Middle East, and Eastern Europe. Civilian populations mobilize, sometimes spontaneously and sometimes in ...
    • GDSCalc: A Web-Based Application for Evaluating Discrete Graph Dynamical Systems 

      Abdelhamid, SHE; Kuhlman, CJ; Marathe, MV; Mortveit, HS; Ravi, SS (PLOS, 2015-08-11)
      Discrete dynamical systems are used to model various realistic systems in network science, from social unrest in human populations to regulation in biological networks. A common approach is to model the agents of a system ...
    • Gene Expression Profiling of Human Vaginal Cells In Vitro Discriminates Compounds with Pro-Inflammatory and Mucosa-Altering Properties: Novel Biomarkers for Preclinical Testing of HIV Microbicide Candidates 

      Zalenskaya, Irina A.; Joseph, Theresa; Bavarva, Jasmin; Yousefieh, Nazita; Jackson, Suzanne S.; Fashemi, Titilayo; Yamamoto, Hidemi S.; Settlage, Robert; Fichorova, Raina N.; Doncel, Gustavo F. (PLOS, 2015-06-08)
      Background Inflammation and immune activation of the cervicovaginal mucosa are considered factors that increase susceptibility to HIV infection. Therefore, it is essential to screen candidate anti-HIV microbicides for ...
    • Gene Ontology annotation of the rice blast fungus, Magnaporthe oryzae 

      Meng, Shaowu; Brown, Douglas E; Ebbole, Daniel J; Torto-Alalibo, Trudy; Oh, Yeon Y; Deng, Jixin; Mitchell, Thomas K.; Dean, Ralph A (2009-02-19)
      Background Magnaporthe oryzae, the causal agent of blast disease of rice, is the most destructive disease of rice worldwide. The genome of this fungal pathogen has been sequenced and an automated annotation has recently ...