Scholarly Works, Institute for Critical Technology and Applied Science (ICTAS)
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Research articles, presentations, and other scholarship
Recent Submissions
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A study on interfacial behaviors of epoxy/graphene oxide derived from pitch-based graphite fibers
(2021-11-12)Graphene oxide (GO) is a versatile material with inherent unique properties that can be used in a wide range of applications. GO is produced from graphitic materials including graphite, and its properties can depend on the ... -
Detectability of the Critically Endangered Araucaria angustifolia Tree Using Worldview-2 Images, Google Earth Engine and UAV-LiDAR
(MDPI, 2021-11-30)The Brazilian Atlantic Forest is a global biodiversity hotspot and has been extensively mapped using satellite remote sensing. However, past mapping focused on overall forest cover without consideration of keystone plant ... -
Establishing an immunocompromised porcine model of human cancer for novel therapy development with pancreatic adenocarcinoma and irreversible electroporation
(Nature Research, 2021-04-07)New therapies to treat pancreatic cancer are direly needed. However, efficacious interventions lack a strong preclinical model that can recapitulate patients’ anatomy and physiology. Likewise, the availability of human ... -
Bubble cloud behavior and ablation capacity for histotripsy generated from intrinsic or artificial cavitation nuclei
(2021-03)The study described here examined the effects of cavitation nuclei characteristics on histotripsy. High-speed optical imaging was used to compare bubble cloud behavior and ablation capacity for histotripsy generated from ... -
3D printed graphene-based self-powered strain sensors for smart tires in autonomous vehicles
(2020-10-26)The transition of autonomous vehicles into fleets requires an advanced control system design that relies on continuous feedback from the tires. Smart tires enable continuous monitoring of dynamic parameters by combining ... -
The PathLinker app: Connect the dots in protein interaction networks
(F1000Research, 2017-01-20)PathLinker is a graph-theoretic algorithm for reconstructing the interactions in a signaling pathway of interest. It efficiently computes multiple short paths within a background protein interaction network from the receptors ... -
Automating the PathLinker app for Cytoscape
(F1000Research, 2018-06-12)PathLinker is a graph-theoretic algorithm originally developed to reconstruct the interactions in a signaling pathway of interest. It efficiently computes multiple short paths within a background protein interaction network ... -
Connectivity Measures for Signaling Pathway Topologies
(Virginia Tech, 2019-03-30)Characterizing cellular responses to different extrinsic signals is an active area of research, and curated pathway databases describe these complex signaling reactions. Here, we revisit a fundamental question in signaling ... -
Antibacterial efficacy of core-shell nanostructures encapsulating gentamicin against an in vivo intracellular Salmonella model
(Dove Medical Press, 2009-01-01)Pluronic based core-shell nanostructures encapsulating gentamicin were designed in this study. Block copolymers of (PAA(+/-)Na-b-(PEO-b-PPO-b-PEO)-b-PAA(+/-)Na) were blended with PAA(-) Na(+) and complexed with the ... -
The assembly of integrated rat intestinal-hepatocyte cultures
(2019-11)The jejunum is the segment of the small intestine responsible for several metabolism and biotransformation functions. In this report, we have cultured rat jejunum explants in vitro and integrated them with hepatocyte ... -
Pulmonary Exposure to Magnéli Phase Titanium Suboxides Results in Significant Macrophage Abnormalities and Decreased Lung Function
(Frontiers, 2019-11-28)Coal is one of the most abundant and economic sources for global energy production. However, the burning of coal is widely recognized as a significant contributor to atmospheric particulate matter linked to deleterious ... -
Nanoparticulate Nickel-Hosting Phases in Sulfidic Environments: Effects of Ferrous Iron and Bacterial Presence on Mineral Formation Mechanism and Solid-Phase Nickel Distribution
(Frontiers, 2019-06-26)The precipitation of nickel with sulfide is an important process governing the bioavailability of Ni in natural waters, and this process has the potential to effectively remove aqueous Ni contaminants in near-surface ... -
Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory
(Beilstein-Institut, 2015)To document the marketing and distribution of nano-enabled products into the commercial marketplace, the Woodrow Wilson International Center for Scholars and the Project on Emerging Nanotechnologies created the Nanotechnology ... -
High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity
(2019-06)Background: Despite promising treatments for breast cancer, mortality rates remain high and treatments for metastatic disease are limited. High-frequency irreversible electroporation (H-FIRE) is a novel tumor ablation ... -
Aerosol microdroplets exhibit a stable pH gradient
(2018-07-10)Suspended aqueous aerosol droplets (< 50 mu m) are microreactors for many important atmospheric reactions. In droplets and other aquatic environments, pH is arguably the key parameter dictating chemical and biological ... -
Continuous synthesis of Zn2Al-CO3 layered double hydroxides: a comparison of bench, pilot and industrial scale syntheses
(2019-04-01)Zn2Al-CO3 was produced continuously at bench (g h(-1)), pilot (100s g h -1) and industrial scale (10s kg h(-1)). Crystal domain length and BET surface area were similar at all three scales although there was a small increase ... -
Sequence verification of synthetic DNA by assembly of sequencing reads
(2013-01)Gene synthesis attempts to assemble user-defined DNA sequences with base-level precision. Verifying the sequences of construction intermediates and the final product of a gene synthesis project is a critical part of the ... -
XTALKDB: a database of signaling pathway crosstalk
(2017-01-04)Analysis of signaling pathways and their crosstalk is a cornerstone of systems biology. Thousands of papers have been published on these topics. Surprisingly, there is no database that carefully and explicitly documents ... -
Effects of internal electrode cooling on irreversible electroporation using a perfused organ model
(Taylor and Francis Ltd, 2018-05-28)Purpose: This study evaluates the effects of active electrode cooling, via internal fluid circulation, on the irreversible electroporation (IRE) lesion, deployed electric current and temperature changes using a perfused ... -
Processing method for grain-oriented lead-free piezoelectric Na0.5Bi0.5TiO3—BaTiO3 ceramics exhibiting giant performance
(United States Patent and Trademark Office, 2017-09-26)Textured ceramic compositions having improved piezoelectric characteristics as compared with their random counterparts are provided. Methods of making the compositions and devices using them are also included. More ...
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