Now showing items 41-50 of 116
Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB. Yaa Mice
IL6 is a multifunctional cytokine that drives terminal B cell differentiation and secretion of immunoglobulins. IL6 also cooperates with IL21 to promote differentiation of CD4+ T follicular helper cells (TFH). Elevated ...
In vitro performance of lipid-PLGA hybrid nanoparticles as an antigen delivery system: lipid composition matters
Due to the many beneficial properties combined from both poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) and liposomes, lipid-PLGA hybrid NPs have been intensively studied as cancer drug delivery systems, bio-imaging ...
Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency
(Nature Publishing Group, 2016-04-27)
Application of genetically engineered (GE) large animals carrying multi-allelic modifications has been hampered by low efficiency in production and extended gestation period compared to rodents. Here, we rapidly generated ...
Investigation of the Chromosome Regions with Significant Affinity for the Nuclear Envelope in Fruit Fly - A Model Based Approach
Three dimensional nuclear architecture is important for genome function, but is still poorly understood. In particular, little is known about the role of the ‘‘boundary conditions’’ – points of attachment between chromosomes ...
Microbial quality of agricultural water in Central Florida
Natural product-based nanomedicine: recent advances and issues
(Dove Medical Press Ltd, 2015-01-01)
Mitotic-Chromosome-Based Physical Mapping of the Culex quinquefasciatus Genome
The genome assembly of southern house mosquito Cx. quinquefasciatus is represented by a high number of supercontigs with no order or orientation on the chromosomes. Although cytogenetic maps for the polytene chromosomes ...