Now showing items 1-10 of 22
A Hidden Transhydrogen Activity of a FMN-Bound Diaphorase under Anaerobic Conditions
Background Redox cofactors of NADH/NADPH participate in many cellular metabolic pathways for facilitating the electron transfer from one molecule to another in redox reactions. Transhydrogenase plays an important role in ...
GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro
(Nature Publishing Group, 2016-10-04)
Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB. Yaa Mice
IL6 is a multifunctional cytokine that drives terminal B cell differentiation and secretion of immunoglobulins. IL6 also cooperates with IL21 to promote differentiation of CD4+ T follicular helper cells (TFH). Elevated ...
Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency
(Nature Publishing Group, 2016-04-27)
Application of genetically engineered (GE) large animals carrying multi-allelic modifications has been hampered by low efficiency in production and extended gestation period compared to rodents. Here, we rapidly generated ...
Urbanization and Income Inequality in Post-Reform China: A Causal Analysis Based on Time Series Data
This paper investigates the potential causal relationship(s) between China’s urbanization and income inequality since the start of the economic reform. Based on the economic theory of urbanization and income distribution, ...
Prediabetes Phenotype Influences Improvements in Glucose Homeostasis with Resistance Training
Purpose To determine if prediabetes phenotype influences improvements in glucose homeostasis with resistance training (RT). Methods Older, overweight individuals with prediabetes (n = 159; aged 60±5 yrs; BMI 33±4 ...
MetaStorm: A Public Resource for Customizable Metagenomics Annotation
Metagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such ...
False positives are statistically inevitable
(Amer Assoc Advancement Science, 2016-02-05)