The Macromolecules Innovation Institute at Virginia Tech (MII) is a university-wide research and education institute, representing a group of faculty, students, and staff dedicated to fostering an interdisciplinary understanding of the macromolecular sciences and technologies. Collectively, we offer a variety of educational, research, and professional interaction opportunities to our students. We also provide industry collaborators with training opportunities through short courses and offer opportunities for unique collaboration through sharing our laboratories, facilities, and expertise.

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Recent Submissions

  • Remote Actuation of Magnetic Nanoparticles For Cancer Cell Selective Treatment Through Cytoskeletal Disruption 

    Master, Alyssa M.; Williams, Philise N.; Pothayee, Nikorn; Pothayee, Nipon; Zhang, Rui; Vishwasrao, Hemant M.; Golovin, Yuri I.; Riffle, Judy S.; Sokolsky, Marina; Kabanov, Alexander V. (Springer Nature, 2016-09-20)
    Motion of micron and sub-micron size magnetic particles in alternating magnetic fields can activate mechanosensitive cellular functions or physically destruct cancer cells. However, such effects are usually observed with ...
  • GSA Tomorrow: An Open Challenge to Promote the Future of Geoscience 

    Dorfler, Kristin M.; Friedrich, Anke M. (Geological Society of America, 2018-11-20)
    The future of geoscience rests on your shoulders. Geologists are passionate about their science and discuss their interests with vigor, firmly understanding why geoscience is as important to society as physiology, agriculture, ...
  • Nanoscale Bacteria‐Enabled Autonomous Drug Delivery System (NanoBEADS) Enhances Intratumoral Transport of Nanomedicine 

    Suh, SeungBeum; Jo, Ami; Traore, Mahama A.; Zhan, Ying; Coutermarsh-Ott, Sheryl L.; Ringel-Scaia, Veronica M.; Allen, Irving C.; Davis, Richey M.; Behkam, Bahareh (Wiley, 2018-12-05)
    Cancer drug delivery remains a formidable challenge due to systemic toxicity and inadequate extravascular transport of nanotherapeutics to cells distal from blood vessels. It is hypothesized that, in absence of an external ...
  • Oil-Impregnated Hydrocarbon-Based Polymer Films 

    Mukherjee, Ranit; Habibi, Mohammad; Rashed, Ziad T.; Berbert, Otacilio; Shi, Xiangke; Boreyko, Jonathan B. (Springer Nature, 2018-08-03)
    Porous surfaces impregnated with a liquid lubricant exhibit minimal contact angle hysteresis with immiscible test liquids, rendering them ideal as self-cleaning materials. Rather than roughening a solid substrate, an ...
  • Folic Acid-Conjugated Cellulose Nanocrystals Show High Folate-Receptor Binding Affinity and Uptake by KB and Breast Cancer Cells 

    Bittleman, Katelyn Rose; Dong, Shuping; Roman, Maren; Lee, Yong Woo (American Chemical Society, 2018-10-24)
    The study evaluates cellulose nanocrystals (CNCs) as nanocarriers for targeted, intracellular delivery of molecular agents. CNCs were labeled with fluorescein-5′-isothiocyanate as an imaging agent and conjugated to folic ...
  • Prediction of Young’s Modulus for Injection Molded Long Fiber Reinforced Thermoplastics 

    Chen, Hongyu; Baird, Donald G. (MDPI, 2018-08-06)
    In this article, the elastic properties of long-fiber injection-molded thermoplastics (LFTs) are investigated by micro-mechanical approaches including the Halpin-Tsai (HT) model and the Mori-Tanaka model based on Eshelby’s ...
  • MII Technical Conference & Review 2018 : From Molecules to Manufacturing 

    Macromolecules Innovation Institute (Virginia Tech, 2018-04-11)
    "From Molecules to Manufacturing" is the 2018 Technical Conference & Review of the Macromolecules Innovation Institute at Virginia Tech. The abstract book contains a schedule of events and abstracts from poster sessions ...
  • Nucleobase-functionalized acrylic ABA triblock copolymers and supramolecular blends 

    Zhang, Keren; Aiba, Motohiro; Fahs, Gregory B.; Hudson, Amanda G.; Chiang, William D.; Moore, Robert B.; Ueda, Mitsuru; Long, Timothy E. (The Royal Society of Chemistry, 2015-01-30)
    Reversible addition-fragmentation chain transfer (RAFT) polymerization afforded the unprecedented synthesis of well-defined acrylic ABA triblock copolymers with nucleobase-functionalized external blocks and a central ...
  • Phosphonium-containing diblock copolymers from living anionic polymerization of 4-diphenylphosphino styrene 

    Schultz, Alison R.; Fahs, Gregory B.; Jangu, Chainika; Chen, Mingtao; Moore, Robert B.; Long, Timothy E. (The Royal Society of Chemistry, 2015-11-20)
    Living anionic polymerization of 4-diphenylphosphino styrene (DPPS) achieved well-defined homopolymers, poly(DPPS-b-S) styrenic block copolymers, and poly(I-b-DPPS) diene-based diblock copolymers with predictable molecular ...
  • Size dependent ion-exchange of large mixed-metal complexes into Nafion® membranes 

    Naughton, Elise M.; Zhang, Mingqiang; Troya, Diego; Brewer, Karen J.; Moore, Robert B. (The Royal Society of Chemistry, 2015-08-18)
    Perfluorosulfonate ionomers have been shown to demonstrate a profound affinity for large cationic complexes, and the exchange of these ions may be used to provide insight regarding Nafion® morphology by contrasting molecular ...
  • Imidazole-containing triblock copolymers with a synergy of ether and imidazolium sites 

    Jangu, Chainika; Wang, Jing-Han Helen; Wang, Dong; Fahs, Gregory B.; Heflin, James R.; Moore, Robert B.; Colby, Ralph H.; Long, Timothy E. (The Royal Society of Chemistry, 2015-03-06)
    Reversible addition-fragmentation chain transfer (RAFT) polymerization enabled the synthesis of well-defined A-BC-A triblock copolymers containing a synergy of pendant ether and imidazolium sites. The soft central BC block ...
  • Imparting functional variety to cellulose ethers via olefin cross-metathesis 

    Dong, Yifan; Edgar, Kevin J. (The Royal Society of Chemistry, 2015-04-09)
    Olefin cross-metathesis is a valuable new approach for imparting functional variety to cellulose ethers. Starting from commercially available ethyl cellulose, terminally unsaturated alkyl groups were appended as metathesis ...
  • Peptide-based hydrogen sulphide-releasing gels 

    Carter, Jennifer M.; Qian, Yun; Foster, Jeffrey C.; Matson, John B. (The Royal Society of Chemistry, 2015-07-20)
    An aromatic peptide amphiphile was designed for delivery of the signaling gas H2S. The peptide self-assembled in water into nanofibers that gelled upon charge screening. The non-toxic gel slowly released H2S over 15 hours, ...
  • Olefin cross-metathesis, a mild, modular approach to functionalized cellulose esters 

    Meng, Xiangtao; Matson, John B.; Edgar, Kevin J. (The Royal Society of Chemistry, 2014-09-02)
    Olefin cross-metathesis has been demonstrated to be a modular pathway for synthesis of a series of functionalized cellulose esters. As a proof of concept, cellulose acetate was acylated with two terminally olefinic acid ...