Virginia Tech's College of Agriculture and Life Sciences has come a long way since Virginia Tech's modest beginnings when Virginia Agricultural and Mechanical College first opened its doors in 1872.

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  • Evaluating the “Drone the Unknown” 4-H Program Curriculum 

    Robbins, Hannah (Virginia Tech, 2018-12-10)
    Within the past ten years, there has been an increase in the demand for more STEM-based programs as is evident by the increase in STEM related careers and opportunities. In order to keep up with these career opportunities ...
  • Department of Horticulture Newsletter, July 2018 

    Unknown author (Virginia Tech, 2018-07)
    This is the monthly newsletter of the Department of Horticulture at Virginia Tech.
  • 4-H Agent Longevity and Youth Participation and Perception: A Case Study 

    Ransdell, Leona (Virginia Tech, 2018-12-13)
    This study examined the influence of the 4-H agent and how the length of time an agent is employed in a community affects the perception of the quality and visibility of the 4-H program based on the theory of Positive Youth ...
  • Removal Efficacy of Nursery Tail-Water Nitrogen and Phosphorus using Ferric aided Zeolite Sieves with or without Bioreactors 

    Birnbaum, Anna P; Owen, James S; Fox, Laurie J; Niemiera, Alex X (Virginia Tech, 2018-12-03)
    Nitrogen (N) and Phosphorus (P) runoff from containerized nurseries contributes to eutrophication in impaired US waterways. Best management practices (BMPs) have been in development for much of the agricultural sector to ...
  • Trends in U.S. Field Corn Plant Population 

    Wright, Mallorie; Thomason, Wade; Reiter, Mark; Broaddus, Michael (Virginia Tech, 2018-11-30)
    This study evaluated the optimum corn plant population for two Hubner corn hybrids at one field site in Virginia. The objective of this study was to compare yield for both hybrids over a range of seeding rates and determine ...
  • SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells 

    Luo, Chaochao; Zhao, Shengguo; Zhang, Muchen; Gao, Yanan; Wang, Jiaqi; Hanigan, Mark D.; Zheng, Nan (Springer Nature, 2018-03-02)
    Amino acids (AA) are one of the key nutrients that regulate cell proliferation and casein synthesis in cow mammary epithelial cells (CMEC), but the mechanism of this regulation is not yet clear. In this study, the effect ...
  • Forest Reclamation of Coal Mined Sites in the Appalachian Region 

    Erwin, Zachary; Daniels, W. Lee; Zipper, Carl; Eick, Matthew (Virginia Tech, 2017-10-02)
    Efforts to restore forested plant communities on coal-mined sites in the eastern USA have increased over the years. Up until the late 1970s, Appalachian coal mining operations frequently transformed forested lands into ...
  • Whole-transcriptome analysis of atrophic ovaries in broody chickens reveals regulatory pathways associated with proliferation and apoptosis 

    Liu, Lingbin; Xiao, Qihai; Gilbert, Elizabeth R.; Cui, Zhifu; Zhao, Xiaoling; Wang, Yan; Yin, Huadong; Li, Diyan; Zhang, Haihan; Zhu, Qing (Springer Nature, 2018-05-08)
    Broodiness in laying hens results in atrophy of the ovary and consequently decreases productivity. However, the regulatory mechanisms that drive ovary development remain elusive. Thus, we collected atrophic ovaries (AO) ...
  • Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter 

    Lee, Andrew H.; Dhingra, Satish K.; Lewis, Ian A.; Singh, Maneesh K.; Siriwardana, Amila; Dalal, Seema; Rubiano, Kelly; Klein, Matthias S.; Baska, Katelynn S.; Krishna, Sanjeev; Klemba, Michael; Roepe, Paul D.; Llinas, Manuel; Garcia, Celia R. S.; Fidock, David A. (Springer Nature, 2018-09-11)
    Plasmodium falciparum multidrug resistance constitutes a major obstacle to the global malaria elimination campaign. Specific mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) mediate resistance ...
  • Crosstalk between the Circadian Clock and Innate Immunity in Arabidopsis 

    Zhang, Chong; Xie, Qiguang; Anderson, Ryan G.; Ng, Gina; Seitz, Nicholas C.; Peterson, Thomas; McClung, C. Robertson; McDowell, John M.; Kong, Dongdong; Kwak, June M.; Lu, Hua (PLOS, 2013-06-06)
    The circadian clock integrates temporal information with environmental cues in regulating plant development and physiology. Recently, the circadian clock has been shown to affect plant responses to biotic cues. To further ...
  • Computational and Biochemical Analysis of the Xanthomonas Effector AvrBs2 and Its Role in the Modulation of Xanthomonas Type Three Effector Delivery 

    Zhao, Bingyu; Dahlbeck, Douglas; Krasileva, Ksenia V.; Fong, Richard W.; Staskawicz, Brian J. (PLOS, 2011-12-01)
    Effectors of the bacterial type III secretion system provide invaluable molecular probes to elucidate the molecular mechanisms of plant immunity and pathogen virulence. In this report, we focus on the AvrBs2 effector protein ...
  • Host ESCRT Proteins Are Required for Bromovirus RNA Replication Compartment Assembly and Function 

    Diaz, Arturo; Zhang, Jiantao; Ollwerther, Abigail; Wang, Xiaofeng; Ahlquist, Paul (PLOS, 2015-03-06)
    Positive-strand RNA viruses genome replication invariably is associated with vesicles or other rearranged cellular membranes. Brome mosaic virus (BMV) RNA replication occurs on perinuclear endoplasmic reticulum (ER) membranes ...
  • A Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers 

    Noble, Geoffrey P.; Wang, Daphne W.; Walsh, Daniel J.; Barone, Justin R.; Miller, Michael B.; Nishina, Koren A.; Li, Sheng; Supattapone, Surachai (PLOS, 2015-06-30)
    Infectious prions contain a self-propagating, misfolded conformer of the prion protein termed PrPSc. A critical prediction of the protein-only hypothesis is that autocatalytic PrPSc molecules should be infectious. However, ...
  • The effector AvrRxo1 phosphorylates NAD in planta 

    Shidore, Teja; Broeckling, Corey D.; Kirkwood, Jay S.; Long, John J.; Miao, Jiamin; Zhao, Bingyu; Leach, Jan E.; Triplett, Lindsay R. (PLOS, 2017-06-19)
    Gram-negative bacterial pathogens of plants and animals employ type III secreted effectors to suppress innate immunity. Most characterized effectors work through modification of host proteins or transcriptional regulators, ...
  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond 

    Van Voorhis, Wesley C.; Adams, John H.; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H.; Alano, Pietro; Alday, Aintzane; Resto, Yesmalie Aleman; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T.; Avery, Simon V.; Avery, Vicky M.; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Juergen; Boucher, Lauren E.; Boyom, Fabrice F.; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R.; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Cassera, Maria Belen; Cheng, Ken Chih-Chien; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L.; Colon-Lopez, Daisy D.; Corbett, Yolanda; Crowther, Gregory J.; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L.; Du, Alan Y.; Duffy, Sandra; El-Sayed, Shimaa Abd El-Salam; Ferdig, Michael T.; Robledo, Jose A. Fernandez; Fidock, David A.; Florent, Isabelle; Fokou, Patrick V. T.; Galstian, Ani; Javier Gamo, Francisco; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M.; Guha, Rajarshi; Guiguemde, W. Armand; Gural, Nil; Guy, R. Kiplin; Hansen, Michael A. E.; Hanson, Kirsten K.; Hemphill, Andrew; van Huijsduijnen, Rob Hooft; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B.; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A.; Jadhav, Ajit; Jensen, Amornrat Naranuntarat; Jensen, Laran T.; Jiang, Rays H. Y.; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P.; Kyle, Dennis E.; Jose Lafuente, Maria; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M.; Li, Fengwu; Little, David; Liu, Liqiong; Llinas, Manuel; Loza, Maria I.; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R.; March, Sandra; McGowan, Sheena; Vera, Iset Medina; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N.; Misra, Raj N.; Moon, Seunghyun; Moore, John P.; Rodrigues da Costa, Francielly Morais; Mueller, Joachim; Muriana, Arantza; Hewitt, Stephen Nakazawa; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K.; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Ngoc Pham; Prats, Sarah; Plouffe, David M.; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J.; Rice, Christopher A.; Rizk, Mohamed Abdo; Ruecker, Andrea; St Onge, Robert; Ferreira, Rafaela Salgado; Samra, Jasmeet; Robinett, Natalie G.; Schlecht, Ulrich; Schmitt, Marjorie; Villela, Filipe Silva; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A.; Soldati, Thierry; Spitzmueller, Andreas; Stamm, Serge Maximilian; Sullivan, David J.; Sullivan, William; Suresh, Sundari; Suzuki, Brian M.; Suzuki, Yo; Swamidass, S. Joshua; Taramelli, Donatella; Tchokouaha, Lauve R. Y.; Theron, Anjo; Thomas, David; Tonissen, Kathryn F.; Townson, Simon; Tripathi, Abhai K.; Trofimov, Valentin; Udenze, Kenneth O.; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M.; Phat Voong Vinh; Hoan Vu; Watanabe, Nao-aki; Weatherby, Kate; White, Pamela M.; Wilks, Andrew F.; Winzeler, Elizabeth A.; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul H. A.; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoit; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A. (PLOS, 2016-07-28)
    A major cause of the paucity of new starting points for drug discovery is the lack of interaction between academia and industry. Much of the global resource in biology is present in universities, whereas the focus of ...
  • Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis 

    Zhang, Zhenlu; He, Guijuan; Han, Gil-Soo; Zhang, Jiantao; Catanzaro, Nicholas; Diaz, Arturo; Wu, Zujian; Carman, George M.; Xie, Lianhui; Wang, Xiaofeng (PLOS, 2018-04-12)
    Replication of positive-strand RNA viruses [(+)RNA viruses] takes place in membrane-bound viral replication complexes (VRCs). Formation of VRCs requires virus-mediated manipulation of cellular lipid synthesis. Here, we ...
  • Alternative Control Methods for Verticillium wilt: A Literature Review 

    Washburn, Morgan (Virginia Tech, 2018-11-30)
    Verticillium wilt (V.albo-atrum and V.dahiae) is a soil-borne fungus that is causing economic losses and lower yields for farmers across the country. The disease has a wide host range and can live in the soil without a ...
  • CALS Ag Tech Newsletter, Summer 2018 

    Unknown author (Virginia Tech, 2018)
    This newsletter highlights successes and accomplishments of the CALS Agricultural Technology program, which offers a concentrated academic experience for individuals pursuing an associate degree in preparation for careers ...
  • Time-Dependent Expression of Arc and Zif268 after Acquisition of Fear Conditioning 

    Lonergan, Mary E.; Gafford, Georgette M.; Jarome, Tiothy J.; Helmstetter, Fred J. (Hindawi, 2010)
    Memory consolidation requires transcription and translation of new protein. Arc, an effector immediate early gene, and zif268, a regulatory transcription factor, have been implicated in synaptic plasticity underlying ...
  • Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in the Amygdala 

    Jarome, Timothy J.; Werner, Craig T.; Kwapis, Janine L.; Helmstetter, Fred J. (PLOS, 2011-09)
    Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear ...

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