College of Agriculture and Life Sciences (CALS): Recent submissions
Now showing items 1-20 of 8994
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College of Agriculture and Life Science (CALS) Faculty Professional Development Resource: Best Practices for Teaching at a Distance
(Virginia Tech, 2021-05-11)Professional development is a necessary component of most jobs and professions. University faculty members who teach in online or hybrid environments need professional development to improve their teaching, stay current ... -
Minicell-based fungal RNAi delivery for sustainable crop protection
(2021-02)Spray-induced gene silencing (SIGS) using topical dsRNA applications has risen as a promising, target-specific, and environmentally friendly disease management strategy against phytopathogenic fungi. However, dsRNA stability, ... -
Single Cell RNA-Seq and Machine Learning Reveal Novel Subpopulations in Low-Grade Inflammatory Monocytes With Unique Regulatory Circuits
(2021-02-23)Subclinical doses of LPS (SD-LPS) are known to cause low-grade inflammatory activation of monocytes, which could lead to inflammatory diseases including atherosclerosis and metabolic syndrome. Sodium 4-phenylbutyrate is a ... -
Peer review as a tool in online instruction, 2021 NACTA presentation resources
(2021-05-10)In the quick transition to online instruction in Spring 2020 due to Covid, instructors bore the brunt of extra work moving content and then figuring out how to assess and manage it. The objectives of this presentation are: ... -
Dog Food Production from Farm to Food Bowl: Evaluating FDA’s Regulatory Oversight and the Impact on Food Safety
(Virginia Tech, 2021-05-06)With the introduction of the Food and Drug Administration’s Food Safety Modernization Act (FSMA) regulatory oversight of dog food production is becoming clearer, and it is important for consumers and manufacturers to ... -
Effect of drought stress on in vitro neutral detergent fiber digestibility of corn for silage
(2021-03)The objective of this study was to determine the effect of drought stress on neutral detergent fiber (NDF) and lignin (LIG) concentrations and on in vitro dry matter digestibility (IVDMD) and in vitro neutral detergent ... -
High-Throughput Screen for Inhibitors of the Type IV Pilus Assembly ATPase PilB
(2021-03)The bacterial type IV pilus (T4P) is a prominent virulence factor in many significant human pathogens, some of which have become increasingly antibiotic resistant. Antivirulence chemotherapeutics are considered a promising ... -
Sulfasalazine decreases mouse cortical hyperexcitability
(Wiley, 2019-05-22)Objective: Currently prescribed antiepileptic drugs (AEDs) are ineffective in treating approximately 30% of epilepsy patients. Sulfasalazine (SAS) is an US Food and Drug Administration (FDA)–approved drug for the treatment ... -
The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients
(Impact Journals, 2019-10-22)Tumor protein 53 (p53) regulates fundamental pathways of cellular growth and differentiation. Aberrant p53 expression in glioblastoma multiforme, a terminal brain cancer, has been associated with worse patient outcomes and ... -
Animal welfare assessment of on-farm euthanasia methods for individual, heavy turkeys
(2021-03)On-farm euthanasia of poultry, including turkeys, may not be possible for most people as birds gain weight; thus alternative mechanical methods have been developed. Our objective was to compare mechanical cervical dislocation ... -
Tryptophan requirement of first-cycle commercial laying hens in peak egg production
(2021-03)An experiment was conducted to evaluate the digestible tryptophan (Trp) requirement of laying hens from 22 to 34 wk of age. A total of 252 Hy-line W-36 laying hens were selected at 16 wk of age and allocated by weight (P ... -
Genome Sequences for Two Acinetobacter baumannii Strains Obtained Using the Unicycler Hybrid Assembly Pipeline
(2021-03)Here, we report a complete genome sequence for Acinetobacter baumannii strain ATCC 17961, with plasmid sequences, and a high-quality (>98% complete) build for A. baumannii strain AB09-003. These genome sequences were ... -
Nox4 mediates skeletal muscle metabolic responses to exercise
(2021-03)Objective: The immediate signals that couple exercise to metabolic adaptations are incompletely understood. Nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) produces reactive oxygen species (ROS) and plays a ... -
Analysis of Shoot Architecture Traits in Edamame Reveals Potential Strategies to Improve Harvest Efficiency
(2021-03-03)Edamame is a type of green, vegetable soybean and improving shoot architecture traits for edamame is important for breeding of high-yield varieties by decreasing potential loss due to harvesting. In this study, we use ... -
Near-infrared spectroscopy outperforms genomics for predicting sugarcane feedstock quality traits
(2021-03-04)The main objectives of this study were to evaluate the prediction performance of genomic and near-infrared spectroscopy (NIR) data and whether the integration of genomic and NIR predictor variables can increase the prediction ... -
Phytochemical Isoliquiritigenin Inhibits Angiogenesis Ex Vivo and Corneal Neovascularization in Mice
(Hilaris, 2014-11-21)Neovascularization is often involved in many diseases and there is no effective treatment for this pathological process. In searching for potential therapies for neovascularization, we screened nineteen pre-selected small ... -
Special Issue “Molecular Mechanisms of Memory Formation and Modification”
(MDPI, 2021-04-16)Memory is vital to human functioning and controls future behavioral responses [...] -
Metatranscriptomic analyses reveal ruminal pH regulates fiber degradation and fermentation by shifting the microbial community and gene expression of carbohydrate-active enzymes
(2021-04-23)Background Volatile fatty acids (VFA) generated from ruminal fermentation by microorganisms provide up to 75% of total metabolizable energy in ruminants. Ruminal pH is an important factor affecting the ... -
Sirt1 coordinates with ERα to regulate autophagy and adiposity
(2021-03-15)Sex difference in adiposity has long been recognized but the mechanism remains incompletely understood. Previous studies suggested that adiposity was regulated by autophagy in response to energy status change. Here, we ...
