Now showing items 1-4 of 4
A Transcriptome Post-Scaffolding Method for Assembling High Quality Contigs
(Hindawi Publishing Corp, 2014-05-28)
With the rapid development of high throughput sequencing technologies, new transcriptomes can be sequenced for little cost with high coverage. Sequence assembly approaches have been modified to meet the requirements for ...
Vindel: a simple pipeline for checking indel redundancy
(Biomed Central Ltd, 2014-11-19)
Background With the advance of next generation sequencing (NGS) technologies, a large number of insertion and deletion (indel) variants have been identified in human populations. Despite much research into variant calling, ...
Quantitative prediction of the effect of genetic variation using hidden Markov models
Background With the development of sequencing technologies, more and more sequence variants are available for investigation. Different classes of variants in the human genome have been identified, including single nucleotide ...
Objective and Comprehensive Evaluation of Bisulfite Short Read Mapping Tools
Background. Large-scale bisulfite treatment and short reads sequencing technology allow comprehensive estimation of methylation states of Cs in the genomes of different tissues, cell types, and developmental stages. Accurate ...