The VA-MD Regional College of Veterinary Medicine is a two-state, three-campus professional school operated by the land-grant universities of Virginia Tech in Blacksburg and the University of Maryland at College Park. The Virginia-Maryland Regional College of Veterinary Medicine is a regional professional school built upon the strong foundations of two of the nation's leading land-grant universities: Virginia Tech in Blacksburg and the University of Maryland at College Park. The College operates three campuses, including the main campus installation at Virginia Tech, the Avrum Gudelsky Veterinary Center at College Park, and the Marion duPont Scott Equine Medical Center in Leesburg.

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  • Lost in translation: Delivering culturally and linguistically appropriate interventions to Hispanic populations 

    Valenzuela, Ivette (2015)
    Hispanics became the United States' largest minority in 2012. Lack of culturally and linguistically appropriate interventions in the Hispanic population at the health-care and community levels increases the risk of negative ...
  • Characterization of Outer Membrane Vesicles from Brucella melitensis and Protection Induced in Mice 

    Avila-Calderon, Eric Daniel; Lopez-Merino, Ahide; Jain, Neeta; Peralta, Humberto; Lopez-Villegas, Edgar Oliver; Sriranganathan, Nammalwar; Boyle, Stephen M.; Witonsky, Sharon; Contreras-Rodriguez, Araceli (Hindawi Publishing Corp, 2011-12-29)
    The outer membrane vesicles (OMVs) from smooth B. melitensis 16 M and a derived rough mutant, VTRM1 strain, were purified and characterized with respect to protein content and induction of immune responses in mice. Proteomic ...
  • Comparative Genomics of Early-Diverging Brucella Strains Reveals a Novel Lipopolysaccharide Biosynthesis Pathway 

    Wattam, Alice R.; Inzana, Thomas J.; Williams, Kelly P.; Mane, Shrinivasrao P.; Shukla, Maulik; Almeida, Nalvo F.; Dickerman, Allan W.; Mason, Steven; Moriyon, Ignacio; O'Callaghan, David; Whatmore, Adrian M.; Sobral, Bruno W.; Tiller, Rebekah V.; Hoffmaster, Alex R.; Frace, Michael A.; De Castro, Cristina; Molinaro, Antonio; Boyle, Stephen M.; De, Barun K.; Setubal, Joao C. (American Society for Microbiology, 2012-11)
    Brucella species are Gram-negative bacteria that infect mammals. Recently, two unusual strains (Brucella inopinata BO1T and B. inopinata-like BO2) have been isolated from human patients, and their similarity to some atypical ...
  • Origin, Evolution, and Genotyping of Emergent Porcine Epidemic Diarrhea Virus Strains in the United States 

    Huang, Yao-Wei; Dickerman, Allan W.; Pineyro, Pablo; Li, Long; Fang, Li; Kiehne, Ross; Opriessnig, Tanja; Meng, Xiang-Jin (American Society for Microbiology, 2013-09)
    Coronaviruses are known to infect humans and other animals and cause respiratory and gastrointestinal diseases. Here we report the emergence of porcine epidemic diarrhea virus (PEDV) in the United States and determination ...
  • A Novel Pathogenic Mammalian Orthoreovirus from Diarrheic Pigs and Swine Blood Meal in the United States 

    Narayanappa, Athmaram Thimmasandra; Sooryanarain, Harini; Deventhiran, Jagadeeswaran; Cao, Dianjun; Venkatachalam, Backiyalakshmi Ammayappan; Kambiranda, Devaiah; LeRoith, Tanya; Heffron, Connie Lynn; Lindstrom, Nicole; Hall, Karen; Jobst, Peter; Sexton, Cary; Meng, Xiang-Jin; Elankumaran, Subbiah (American Society for Microbiology, 2015-05)
    Since May 2013, outbreaks of porcine epidemic diarrhea have devastated the U.S. swine industry, causing immense economic losses. Two different swine enteric coronaviruses (porcine epidemic diarrhea virus and Delta coronavirus) ...
  • Capsular Polysaccharide Interferes with Biofilm Formation by Pasteurella multocida Serogroup A 

    Petruzzi, Briana; Briggs, Robert E.; Swords, W. Edward; De Castro, Cristina; Molinaro, Antonio; Inzana, Thomas J. (American Society for Microbiology, 2017-11)
    Pasteurella multocida is an important multihost animal and zoonotic pathogen that is capable of causing respiratory and multisystemic diseases, bacteremia, and bite wound infections. The glycosaminoglycan capsule of P. ...
  • A 6-Nucleotide Regulatory Motif within the AbcR Small RNAs of Brucella abortus Mediates Host-Pathogen Interactions 

    Sheehan, Lauren M.; Caswell, Clayton C. (American Society for Microbiology, 2017-05)
    In Brucella abortus, two small RNAs (sRNAs), AbcR1 and AbcR2, are responsible for regulating transcripts encoding ABC-type transport systems. AbcR1 and AbcR2 are required for Brucella virulence, as a double chromosomal ...
  • A versatile computational pipeline for bacterial genome annotation improvement and comparative analysis, with Brucella as a use case 

    Yu, G. X.; Snyder, E. E.; Boyle, S. M.; Crasta, O. R.; Czar, M.; Mane, S. P.; Purkayastha, A.; Sobral, B.; Setubal, J. C. (2007-06)
    We present a bacterial genome computational analysis pipeline, called GenVar. The pipeline, based on the program GeneWise, is designed to analyze an annotated genome and automatically identify missed gene calls and sequence ...
  • PATRIC: The VBI PathoSystems Resource Integration Center 

    Snyder, E. E.; Kampanya, N.; Lu, J.; Nordberg, E. K.; Karur, H. R.; Shukla, M.; Soneja, J.; Tian, Y.; Xue, T.; Yoo, H.; Zhang, F.; Dharmanolla, C.; Dongre, N. V.; Gillespie, J. J.; Hamelius, J.; Hance, M.; Huntington, K. I.; Jukneliene, D.; Koziski, J.; Mackasmiel, L.; Mane, S. P.; Nguyen, V.; Purkayastha, A.; Shallom, J.; Yu, G.; Guo, Y.; Gabbard, J.; Hix, D.; Azad, A. F.; Baker, S. C.; Boyle, S. M.; Khudyakov, Y.; Meng, X. J.; Rupprecht, C.; Vinje, J.; Crasta, O. R.; Czar, M. J.; Dickerman, A.; Eckart, J. D.; Kenyon, R.; Will, R.; Setubal, J. C.; Sobral, B. W. S. (2007-01)
    The PathoSystems Resource Integration Center (PATRIC) is one of eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infection Diseases (NIAID) to create a data and analysis resource ...
  • CAGm: A repository of germline microsatellite variations in the 1000 genomes project 

    Kinney, N.; Titus-Glover, K.; Wren, J.D.; Varghese, R.T.; Michalak, P.; Liao, H.; Anandakrishnan, R.; Pulenthiran, A.; Kang, L.; Garner, H.R. (Oxford University Press, 2019-01-08)
    The human genome harbors an abundance of repetitive DNA; however, its function continues to be debated. Microsatellites-a class of short tandem repeat-are established as an important source of genetic variation. Array ...
  • Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains 

    Suarez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Castillo-Zeledon, Amanda; Jimenez-Rojas, Cesar; Roop, R. Martin, II; Comerci, Diego J.; Barquero-Calvo, Elias; Chacon-Diaz, Carlos; Caswell, Clayton C.; Baker, Kate S.; Chaves-Olarte, Esteban; Thomson, Nicholas R.; Moreno, Edgardo; Letesson, Jean J.; De Bolle, Xavier; Guzman-Verri, Caterina (Frontiers, 2016-09-29)
    Brucellosis is a bacterial infectious disease affecting a wide range of mammals and a neglected zoonosis caused by species of the genetically homogenous genus Brucella. As in most studies on bacterial diseases, research ...
  • Rice Bran and Probiotics Alter the Porcine Large Intestine and Serum Metabolomes for Protection against Human Rotavirus Diarrhea 

    Nealon, Nora Jean; Yuan, Lijuan; Yang, Xingdong; Ryan, Elizabeth P. (Frontiers, 2017-04-21)
    Human rotavirus (HRV) is a leading cause of severe childhood diarrhea, and there is limited vaccine efficacy in the developing world. Neonatal gnotobiotic pigs consuming a prophylactic synbiotic combination of probiotics ...
  • Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice 

    Catanzaro, Kelly C. Freudenberger; Champion, Anna E.; Mohapatra, Nrusingh; Cecere, Thomas; Inzana, Thomas J. (Frontiers, 2017-05-30)
    Francisella tularensis is a Gram-negative bacterium and the etiologic agent of tularemia. F. tularensis may appear encapsulated when examined by transmission electron microscopy (TEM), which is due to production of an ...
  • Twenty-Eighth Annual Research Symposium, Virginia-Maryland College of Veterinary Medicine, March 16, 2017 

    Unknown author (Virginia Tech, 2017-03-16)
    Each year the Virginia-Maryland College of Veterinary Medicine hosts this event to support the College’s mission of providing education to a diverse population of professional and postgraduate students in preparation for ...
  • Twenty-Ninth Annual Research Symposium, Virginia-Maryland College of Veterinary Medicine, March 15, 2018 

    Unknown author (Virginia Tech, 2018-03-15)
    The twenty-ninth Annual Research Symposium was held on Thursday, March 15, 2018, at the main college complex on the Virginia Tech campus. The event showcased graduate student research and featured keynote speakers Dr. ...
  • Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates 

    Yablonovitch, Arielle L.; Fu, Jeremy; Li, Kexin; Mahato, Simpla; Kang, Lin; Rashkovetsky, Eugenia; Korol, Abraham B.; Tang, Hua; Michalak, Pawel; Zelhof, Andrew C.; Nevo, Eviatar; Li, Jin Billy (Springer Nature, 2017-11-17)
    Determining the mechanisms by which a species adapts to its environment is a key endeavor in the study of evolution. In particular, relatively little is known about how transcriptional processes are fine-tuned to adjust ...
  • Expression and activity of the urokinase plasminogen activator system in canine primary brain tumors 

    Rossmeisl, John H.; Hall-Manning, Kelli; King, Jamie N.; Davalos, Rafael V.; Debinski, Waldemar; Elankumaran, Subbiah (Dove Press, 2017-04-12)
    Background: The expression of the urokinase plasminogen activator receptor (uPAR), a glycosylphosphatidylinositol-anchored protein family member, and the activity of its ligand, urokinase-type plasminogen activator (uPA), ...
  • Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain 

    Rossmeisl, John H., Jr.; Garcia, Paulo A.; Robertson, John L.; Ellis, Thomas L.; Davalos, Rafael V. (Korean Society of Veterinary Science, 2013)
    This study describes the neuropathologic features of normal canine brain ablated with non-thermal irreversible electroporation (N-TIRE). The parietal cerebral cortices of four dogs were treated with N-TIRE using a ...
  • Canine Butterfly Glioblastomas: a Neuroradiological Review 

    Rossmeisl, John H.; Clapp, Kemba; Pancotto, Theresa E.; Emch, Samantha; Robertson, John L.; Debinski, Waldemar (Frontiers, 2016-05-19)
    In humans, high-grade gliomas may infiltrate across the corpus callosum resulting in bihemispheric lesions that may have symmetrical, winged-like appearances. This particular tumor manifestation has been coined a “butterfly” ...
  • Optic nerve astrocytoma in a dog 

    Rozov, Orr; Piñyero, Pablo E.; Zimmerman, Kurt L.; Herring, Ian P.; Matusow, Rachel; Rossmeisl, John H.; Jortner, Bernard S.; Dreyfus, Jennifer (Wiley, 2016)
    Intraocular neoplasms in dogs are uncommon in comparison with other anatomic locations [1–4]. Over 75% of these cases are attributed to melanocytic neoplasia [1]. A majority of the remaining cases (~22%) are comprised of ...

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