This presentation gives an overview of the Sustainable Agriculture and Natural Resource Management Collaborative Research Support Program (SANREM CRSP). The SANREM CRSP utilizes a systems approach to promote many goals including the improvement of agricultural productivity, the empowerment of smallholders, and the promotion of sustainable development. This presentation shows the different components, partners, and structure of the SANREM CRSP, the extent of capacity building efforts, and the long-term research activities for Phase IV.