Virginia Tech
    • Log in
    View Item 
    •   VTechWorks Home
    • Virginia Tech Patents
    • Virginia Tech Patents
    • View Item
    •   VTechWorks Home
    • Virginia Tech Patents
    • Virginia Tech Patents
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Porcine torque teno virus vaccines and diagnosis

    Thumbnail
    View/Open
    9228242.pdf (6.959Mb)
    Downloads: 138
    Publication Date
    2016-01-05
    Filing Date
    2010-08-23
    Inventor
    Meng, Xiang-Jin
    Huang, Yaowei
    Metadata
    Show full item record
    Abstract
    The present invention provides four purified preparation containing a polynucleic acid molecule encoding porcine Torque teno virus (PTTV) genotypes or subtypes PTTV1a-VA, PTTV1b-VA, PTTV2b-VA, and PTTV2c-VA. The present invention also provides infectious DNA clones, biologically functional plasmid or viral vector containing the infectious nucleic acid genome molecule of the same. The present invention further provides live, attenuated, vector-expressed and purified recombinant capsid subunit or killed viral vaccines for protection against PTTV infection. The present invention additionally provides subunit vaccines comprising PTTV specific gene products, especially ORF1 capsid gene product for protection against PTTV infection. Further, the present invention provides methods for diagnosing PTTV infection via polymerase chain reaction (PCR) using specific primer for PTTV1, PTTV2, and individual PTTV1 genotypes. Finally, the present invention provides methods for diagnosing PTTV infection via immunological methods, e.g., enzyme-linked immunoabsorbent assay (ELISA) and Western blot using PTTV specific antigens for detecting serum PTTV specific antibodies.
    Assignee
    Virginia Tech Intellectual Properties, Inc.
    Patent Number
    9228242
    Application Number
    12861378
    Source URL
    http://pimg-fpiw.uspto.gov/fdd/42/282/092/0.pdf
    Primary/U.S. Class
    1/1
    Other/U.S. Class
    CPC Class
    Patent Type
    utility
    URI
    http://hdl.handle.net/10919/72767
    Collections
    • Virginia Tech Patents [689]

    If you believe that any material in VTechWorks should be removed, please see our policy and procedure for Requesting that Material be Amended or Removed. All takedown requests will be promptly acknowledged and investigated.

    Virginia Tech | University Libraries | Contact Us
     

     

    VTechWorks

    AboutPoliciesHelp

    Browse

    All of VTechWorksCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Log inRegister

    Statistics

    View Usage Statistics

    If you believe that any material in VTechWorks should be removed, please see our policy and procedure for Requesting that Material be Amended or Removed. All takedown requests will be promptly acknowledged and investigated.

    Virginia Tech | University Libraries | Contact Us