Browsing Destination Area: Adaptive Brain and Behavior (ABB) by Title
Now showing items 1-20 of 394
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A 3-D Finite-Element Minipig Model to Assess Brain Biomechanical Responses to Blast Exposure
(Frontiers, 2021-12-17)Despite years of research, it is still unknown whether the interaction of explosion-induced blast waves with the head causes injury to the human brain. One way to fill this gap is to use animal models to establish “scaling ... -
A 4-year longitudinal neuroimaging study of cognitive control using latent growth modeling: developmental changes and brain-behavior associations
(2021-08-15)Despite theoretical models suggesting developmental changes in neural substrates of cognitive control in adolescence, empirical research has rarely examined intraindividual changes in cognitive control-related brain ... -
7.0-T Magnetic Resonance Imaging Characterization of Acute Blood-Brain-Barrier Disruption Achieved with Intracranial Irreversible Electroporation
(PLOS, 2012-11-30)The blood-brain-barrier (BBB) presents a significant obstacle to the delivery of systemically administered chemotherapeutics for the treatment of brain cancer. Irreversible electroporation (IRE) is an emerging technology ... -
A Molecular Mechanism Regulating the Timing of Corticogeniculate Innervation
(Elsevier, 2013-11-14)Neural circuit formation demands precise timing of innervation by different classes of axons. However, the mechanisms underlying such activity remain largely unknown. In the dorsal lateral geniculate nucleus (dLGN), axons ... -
Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model
(Elsevier, 2018-07-10)Down syndrome (DS) is a genetic disorder that causes cognitive impairment. The staggering effects associated with an extra copy of human chromosome 21 (HSA21) complicates mechanistic understanding of DS pathophysiology. ... -
Aberrant early growth of individual trigeminal sensory and motor axons in a series of mouse genetic models of 22q11.2 deletion syndrome
(2020-09-15)We identified divergent modes of initial axon growth that prefigure disrupted differentiation of the trigeminal nerve (CN V), a cranial nerve essential for suckling, feeding and swallowing (S/F/S), a key innate behavior ... -
Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments
(2020-09-21)Brain injury resulting from repeated mild traumatic insult is associated with cognitive dysfunction and other chronic co-morbidities. The current study tested the effects of aberrant neurogenesis in a mouse model of repeated ... -
Acetylcholine Receptor Activation as a Modulator of Glioblastoma Invasion
(MDPI, 2019-10-05)Grade IV astrocytomas, or glioblastomas (GBMs), are the most common malignant primary brain tumor in adults. The median GBM patient survival of 12–15 months has remained stagnant, in spite of treatment strategies, ... -
Acoustic differences between healthy and depressed people: a cross-situation study
(2019-10-15)Background Abnormalities in vocal expression during a depressed episode have frequently been reported in people with depression, but less is known about if these abnormalities only exist in special situations. In addition, ... -
Active inference and agency: optimal control without cost functions
(Springer, 2012-08-03)This paper describes a variational free-energy formulation of (partially observable) Markov decision problems in decision making under uncertainty. We show that optimal control can be cast as active inference. In active ... -
Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in the Amygdala
(PLOS, 2011-09)Protein degradation through the ubiquitin-proteasome system [UPS] plays a critical role in some forms of synaptic plasticity. However, its role in memory formation in the amygdala, a site critical for the formation of fear ... -
Adaptive Brain and Behavior Across the Lifespan
(Virginia Tech, 2016-05)Our aim is to understand adaptation and improve human lives in various contexts. Inequalities and environments in which people live affect their health and behavior — and their success of remaining healthy for a lifetime. ... -
Adolescent Emotionality and Emotion Regulation in the Context of Parent Emotion Socialization Among Adolescents with Neurodevelopmental Disorders: A Call to Action with Pilot Data
(Springer, 2021-06-30)To date, only three studies have examined the role of emotion socialization in the emotional functioning of youth with neurodevelopmental disorders. As such, this review article with pilot data sought to provide a call to ... -
Age differences in functional network reconfiguration with working memory training
(2021-04-15)Demanding cognitive functions like working memory (WM) depend on functional brain networks being able to communicate efficiently while also maintaining some degree of modularity. Evidence suggests that aging can disrupt ... -
Age, but Not Sex, Modulates Foxp3 Expression in the Rat Brain across Development
(Elsevier, 2020)The interconnectivity between brain development and the immune system has become an area of interest for many neuroscientists. However, to date, a limited number of known immune mediators of the peripheral nervous system ... -
Age-Related Intrinsic Functional Connectivity Changes of Locus Coeruleus from Childhood to Older Adults
(MDPI, 2021-11-10)The locus coeruleus is critical for selective information processing by modulating the brain’s connectivity configuration. Increasingly, studies have suggested that LC controls sensory inputs at the sensory gating stage. ... -
Aging and network properties: Stability over time and links with learning during working memory training
(Frontiers Media S.A., 2018-01-04)Growing evidence suggests that healthy aging affects the configuration of large-scale functional brain networks. This includes reducing network modularity and local efficiency. However, the stability of these effects over ... -
Aging into Perceptual Control: A Dynamic Causal Modeling for fMRI Study of Bistable Perception
(Frontiers, 2016-03-31)Aging is accompanied by stereotyped changes in functional brain activations, for example a cortical shift in activity patterns from posterior to anterior regions is one hallmark revealed by functional magnetic resonance ... -
Aging, resistance training, and diabetes prevention.
(2010-12-15)With the aging of the baby-boom generation and increases in life expectancy, the American population is growing older. Aging is associated with adverse changes in glucose tolerance and increased risk of diabetes; the ... -
Agrin and Synaptic Laminin Are Required to Maintain Adult Neuromuscular Junctions
(PLOS, 2012-10-03)As synapses form and mature the synaptic partners produce organizing molecules that regulate each other’s differentiation and ensure precise apposition of pre- and post-synaptic specializations. At the skeletal neuromuscular ...
