Drug-Susceptible and Multidrug-Resistant Mycobacterium tuberculosis in a Single Patient
Houpt, Eric R.
Heysell, Scott K.
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A patient who had initial infection with mixed strains of drug-susceptible and multidrug-resistant tuberculosis was presumed to have acquired drug resistance before confirmation that sequential strains were genotypically distinct. Transmitted infection with mixed strains is likely underappreciated; identifying these infections requires spoligotyping and whole-genome sequencing.