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Understanding and applying the RE-AIM framework: Clarifications and resources

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dc.contributor.authorHoltrop, Jodi Summersen
dc.contributor.authorEstabrooks, Paul A.en
dc.contributor.authorGaglio, Bridgeten
dc.contributor.authorHarden, Samantha M.en
dc.contributor.authorKessler, Rodger S.en
dc.contributor.authorKing, Diane K.en
dc.contributor.authorKwan, Bethany M.en
dc.contributor.authorOry, Marcia G.en
dc.contributor.authorRabin, Borsika A.en
dc.contributor.authorShelton, Rachel C.en
dc.contributor.authorGlasgow, Russell E.en
dc.date.accessioned2021-11-23T14:29:30Zen
dc.date.available2021-11-23T14:29:30Zen
dc.date.issued2021-05-14en
dc.description.abstractIntroduction: Understanding, categorizing, and using implementation science theories, models, and frameworks is a complex undertaking. The issues involved are even more challenging given the large number of frameworks and that some of them evolve significantly over time. As a consequence, researchers and practitioners may be unintentionally mischaracterizing frameworks or basing actions and conclusions on outdated versions of a framework. Methods: This paper addresses how the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework has been described, summarizes how the model has evolved over time, and identifies and corrects several misconceptions. Results: We address 13 specific areas where misconceptions have been noted concerning the use of RE-AIM and summarize current guidance on these issues. We also discuss key changes to RE-AIM over the past 20 years, including the evolution to Pragmatic Robust Implementation and Sustainability Model, and provide resources for potential users to guide application of the framework. Conclusions: RE-AIM and many other theories and frameworks have evolved, been misunderstood, and sometimes been misapplied. To some degree, this is inevitable, but we conclude by suggesting some actions that reviewers, framework developers, and those selecting or applying frameworks can do to prevent or alleviate these problems.en
dc.description.notesDrs. Glasgow and Holtrop's contributions are supported in part by grant #P50CA244688 from the National Cancer Institute. Dr. Estabrooks' contributions supported by U54 GM115458-01 Great Plains IDEA CTR.en
dc.description.sponsorshipNational Cancer InstituteUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Cancer Institute (NCI) [P50CA244688]; [U54 GM115458-01]en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1017/cts.2021.789en
dc.identifier.eissn2059-8661en
dc.identifier.issue1en
dc.identifier.othere126en
dc.identifier.pmid34367671en
dc.identifier.urihttp://hdl.handle.net/10919/106719en
dc.identifier.volume5en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectRE-AIMen
dc.subjectimplementation science frameworken
dc.subjectgeneralizationen
dc.subjectPRISMen
dc.subjectcontexten
dc.subjectadaptationen
dc.subjectSustainabilityen
dc.titleUnderstanding and applying the RE-AIM framework: Clarifications and resourcesen
dc.title.serialJournal of Clinical and Translational Scienceen
dc.typeArticle - Refereeden
dc.type.dcmitypetexten

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