Development of an individual-based model for polioviruses: implications of the selection of network type and outcome metrics

dc.contributorVirginia Techen
dc.contributor.authorRahmandad, Hazhiren
dc.contributor.authorHu, K.en
dc.contributor.authorTebbens, R. J. D.en
dc.contributor.authorThompson, Kimberly M.en
dc.contributor.departmentIndustrial and Systems Engineeringen
dc.date.accessed2014-07-15en
dc.date.accessioned2014-07-21T15:49:37Zen
dc.date.available2014-07-21T15:49:37Zen
dc.date.issued2011-06-01en
dc.description.abstractWe developed an individual-based (IB) model to explore the stochastic attributes of state transitions, the heterogeneity of the individual interactions, and the impact of different network structure choices on the poliovirus transmission process in the context of understanding the dynamics of outbreaks. We used a previously published differential equation-based model to develop the IB model and inputs. To explore the impact of different types of networks, we implemented a total of 26 variations of six different network structures in the IB model. We found that the choice of network structure plays a critical role in the model estimates of cases and the dynamics of outbreaks. This study provides insights about the potential use of an IB model to support policy analyses related to managing the risks of polioviruses and shows the importance of assumptions about network structure.en
dc.description.sponsorshipWorld Health Organization Polio Research Committeeen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationRahmandad, H.; Hu, K.; Tebbens, R. J. D.; Thompson, K. M., "Development of an individual-based model for polioviruses: implications of the selection of network type and outcome metrics," Epidemiol. Infect. (2011), 139, 836-848. DOI: 10.1017/s0950268810001676en
dc.identifier.doihttps://doi.org/10.1017/s0950268810001676en
dc.identifier.issn0950-2688en
dc.identifier.urihttp://hdl.handle.net/10919/49629en
dc.identifier.urlhttp://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8266579&fulltextType=RA&fileId=S0950268810001676en
dc.language.isoenen
dc.publisherCambridge University Pressen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectDisease transmissionen
dc.subjectIndividual-based modelen
dc.subjectOutbreak responseen
dc.subjectPoliovirusen
dc.subjectInfectious diseasesen
dc.subjectPandemic influenzaen
dc.subjectRisk-managementen
dc.subjectSpreaden
dc.subjectPoliomyelitisen
dc.subjectEpidemiologyen
dc.subjectDynamicsen
dc.subjectPolioen
dc.subjectOutbreaksen
dc.subjectEradicationen
dc.subjectPublic, environmental & occupational healthen
dc.subjectInfectious diseasesen
dc.titleDevelopment of an individual-based model for polioviruses: implications of the selection of network type and outcome metricsen
dc.title.serialEpidemiology and Infectionen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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