Irreversible electroporation to create tissue scaffolds

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorDavalos, Rafael V.en
dc.date.accessed2021-03-23en
dc.date.accessioned2021-03-25T18:15:43Zen
dc.date.available2021-03-25T18:15:43Zen
dc.date.filed2017-02-03en
dc.date.issued2019-05-14en
dc.description.abstractThe present invention provides engineered tissue scaffolds, engineered tissues, and methods of using them. The scaffolds and tissues are derived from natural tissues and are created using non-thermal irreversible electroporation (IRE). Use of IRE allows for ablation of cells of the tissue to be treated, but allows vascular and neural structures to remain essentially unharmed. Use of IRE thus permits preparation of thick tissue scaffolds and tissues due to the presence of vasculature within the scaffolds. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation.en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber15423986en
dc.identifier.patentnumber10286108en
dc.identifier.urihttp://hdl.handle.net/10919/102832en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/08/861/102/0.pdfen
dc.language.isoenen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcA61L27/3691en
dc.subject.cpcA61K35/12en
dc.subject.cpcA61L27/3604en
dc.subject.cpcA61L27/3625en
dc.subject.cpcA61L27/3633en
dc.subject.cpcA61L27/38en
dc.subject.cpcA61L2430/28en
dc.subject.cpcA61L2430/40en
dc.subject.cpcC12N5/0068en
dc.subject.cpcC12N13/00en
dc.subject.cpcC12N2533/90en
dc.titleIrreversible electroporation to create tissue scaffoldsen
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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