PATRIC, the bacterial bioinformatics database and analysis resource

Simple item page
dc.contributor.authorWattam, Alice R.en
dc.contributor.authorAbraham, Daviden
dc.contributor.authorDalay, Oralen
dc.contributor.authorDisz, Terry L.en
dc.contributor.authorDriscoll, Timothyen
dc.contributor.authorGabbard, Joseph L.en
dc.contributor.authorGillespie, Joseph J.en
dc.contributor.authorGough, Rogeren
dc.contributor.authorHix, Deborahen
dc.contributor.authorKenyon, Ronald W.en
dc.contributor.authorMachi, Dustinen
dc.contributor.authorMao, Chunhongen
dc.contributor.authorNordberg, Eric K.en
dc.contributor.authorOlson, Roberten
dc.contributor.authorOverbeek, Rossen
dc.contributor.authorPusch, Gordon D.en
dc.contributor.authorShukla, Mauliken
dc.contributor.authorSchulman, Julieen
dc.contributor.authorStevens, Rick L.en
dc.contributor.authorSullivan, Daniel E.en
dc.contributor.authorVonstein, Veronikaen
dc.contributor.authorWarren, Andrew S.en
dc.contributor.authorWill, Rebeccaen
dc.contributor.authorWilson, Meredith J. C.en
dc.contributor.authorYoo, Hyunseungen
dc.contributor.authorZhang, Chengdongen
dc.contributor.authorZhang, Yanen
dc.contributor.authorSobral, Brunoen
dc.contributor.departmentFralin Life Sciences Instituteen
dc.contributor.departmentIndustrial and Systems Engineeringen
dc.date.accessioned2019-04-12T14:55:19Zen
dc.date.available2019-04-12T14:55:19Zen
dc.date.issued2014-01en
dc.description.abstractThe Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e. g. genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures and sequence typing data] and associated metadata. Datatypes are summarized for individual genomes and across taxonomic levels. All genomes in PATRIC, currently more than 10 000, are consistently annotated using RAST, the Rapid Annotations using Subsystems Technology. Summaries of different data types are also provided for individual genes, where comparisons of different annotations are available, and also include available transcriptomic data. PATRIC provides a variety of ways for researchers to find data of interest and a private workspace where they can store both genomic and gene associations, and their own private data. Both private and public data can be analyzed together using a suite of tools to perform comparative genomic or transcriptomic analysis. PATRIC also includes integrated information related to disease and PPIs. All the data and integrated analysis and visualization tools are freely available. This manuscript describes updates to the PATRIC since its initial report in the 2007 NAR Database Issue.en
dc.description.notesFunding for open access charge: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Service [Contract No. HHSN272200900040C].en
dc.description.sponsorshipNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Service [HHSN272200900040C]en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1093/nar/gkt1099en
dc.identifier.eissn1362-4962en
dc.identifier.issn0305-1048en
dc.identifier.issueD1en
dc.identifier.pmid24225323en
dc.identifier.urihttp://hdl.handle.net/10919/88954en
dc.identifier.volume42en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectmolecular interaction databaseen
dc.subjectantibiotic-resistance genesen
dc.subjectinfectious-diseasesen
dc.subjectstructural genomicsen
dc.subjectpathogen databaseen
dc.subjectvirulence factorsen
dc.subjectdata setsen
dc.subjectupdateen
dc.subjectintegrationen
dc.subjecttoolsen
dc.titlePATRIC, the bacterial bioinformatics database and analysis resourceen
dc.title.serialNucleic Acids Researchen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
gkt1099.pdf
Size:
17.82 MB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections

Scholarly Works, Fralin Life Sciences Institute
Scholarly Works, Industrial and Systems Engineering