Electroporation with cooling to treat tissue

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorDavalos, Rafael V.en
dc.contributor.inventorRobertson, John L.en
dc.contributor.inventorGarcia, Paulo A.en
dc.contributor.inventorRossmeisl, John H. Jr.en
dc.contributor.inventorNeal, II, Robert E.en
dc.date.accessed2021-03-23en
dc.date.accessioned2021-03-25T18:15:45Zen
dc.date.available2021-03-25T18:15:45Zen
dc.date.filed2015-02-20en
dc.date.issued2019-04-02en
dc.description.abstractThe present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. Included is a method of treating tissue with electrical energy, the method comprising: delivering electrical energy to tissue using one or more electroporation devices comprising one or more electrodes; and cooling the tissue, surrounding tissue, one or more of the electrodes, or one or more of the electroporation devices to minimize heating. In embodiments, the invention can be used to treat solid tumors, such as brain tumors, and in some embodiments, exemplary methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors.en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber14627046en
dc.identifier.patentnumber10245105en
dc.identifier.urihttp://hdl.handle.net/10919/102839en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/05/451/102/0.pdfen
dc.languageenen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcA61B18/1477en
dc.subject.cpcA61B18/1206en
dc.subject.cpcA61N1/327en
dc.subject.cpcA61B2018/00446en
dc.subject.cpcA61B2018/00613en
dc.subject.cpcA61N1/05en
dc.subject.cpcC12N13/00en
dc.titleElectroporation with cooling to treat tissueen
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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