Supramolecular complexes as photoactivated DNA cleavage agents

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorBrewer, Karen J.en
dc.contributor.inventorSwavey, Shawnen
dc.date.accessed2016-08-19en
dc.date.accessioned2016-08-24T17:54:54Zen
dc.date.available2016-08-24T17:54:54Zen
dc.date.filed2005-07-20en
dc.date.issued2009-11-03en
dc.description.abstractThe invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging π-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber11184840en
dc.identifier.patentnumber7612057en
dc.identifier.urihttp://hdl.handle.net/10919/72622en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/57/120/076/0.pdfen
dc.language.isoen_USen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcC07F15/0026en
dc.subject.cpcC07F15/0053en
dc.subject.cpcC07F15/008en
dc.subject.uspc514/188en
dc.subject.uspcother514/184en
dc.titleSupramolecular complexes as photoactivated DNA cleavage agentsen
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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