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A communal catalogue reveals Earth's multiscale microbial diversity

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dc.contributor.authorThompson, Luke R.en
dc.contributor.authorSanders, Jon G.en
dc.contributor.authorMcDonald, Danielen
dc.contributor.authorAmir, Amnonen
dc.contributor.authorLadau, Joshuaen
dc.contributor.authorLocey, Kenneth J.en
dc.contributor.authorPrill, Robert J.en
dc.contributor.authorTripathi, Anupriyaen
dc.contributor.authorGibbons, Sean M.en
dc.contributor.authorAckermann, Gailen
dc.contributor.authorNavas-Molina, Jose A.en
dc.contributor.authorJanssen, Stefanen
dc.contributor.authorKopylova, Evgueniaen
dc.contributor.authorVazquez-Baeza, Yoshikien
dc.contributor.authorGonzalez, Antonioen
dc.contributor.authorMorton, James T.en
dc.contributor.authorMirarab, Siavashen
dc.contributor.authorXu, Zhenjiang Zechen
dc.contributor.authorJiang, Lingjingen
dc.contributor.authorHaroon, Mohamed F.en
dc.contributor.authorKanbar, Jaden
dc.contributor.authorZhu, Qiyunen
dc.contributor.authorSong, Se Jinen
dc.contributor.authorKosciolek, Tomaszen
dc.contributor.authorBokulich, Nicholas A.en
dc.contributor.authorLefler, Joshuaen
dc.contributor.authorBrislawn, Colin J.en
dc.contributor.authorHumphrey, Gregoryen
dc.contributor.authorOwens, Sarah M.en
dc.contributor.authorHampton-Marcell, Jarraden
dc.contributor.authorBerg-Lyons, Donnaen
dc.contributor.authorMcKenzie, Valerieen
dc.contributor.authorFierer, Noahen
dc.contributor.authorFuhrman, Jed A.en
dc.contributor.authorClauset, Aaronen
dc.contributor.authorStevens, Rick L.en
dc.contributor.authorShade, Ashleyen
dc.contributor.authorPollard, Katherine S.en
dc.contributor.authorGoodwin, Kelly D.en
dc.contributor.authorJansson, Janet K.en
dc.contributor.authorGilbert, Jack A.en
dc.contributor.authorKnight, Roben
dc.contributor.authorRivera, Jose L. Agostoen
dc.contributor.authorAl-Moosawi, Lisaen
dc.contributor.authorAlverdy, Johnen
dc.contributor.authorAmato, Katherine R.en
dc.contributor.authorAndras, Jasonen
dc.contributor.authorAngenent, Largus T.en
dc.contributor.authorAntonopoulos, Dionysios A.en
dc.contributor.authorApprill, Amyen
dc.contributor.authorArmitage, Daviden
dc.contributor.authorBallantine, Kateen
dc.contributor.authorBarta, Jirien
dc.contributor.authorBaum, Julia K.en
dc.contributor.authorBerry, Allisonen
dc.contributor.authorBhatnagar, Ashishen
dc.contributor.authorBhatnagar, Monicaen
dc.contributor.authorBiddle, Jennifer F.en
dc.contributor.authorBittner, Lucieen
dc.contributor.authorBoldgiv, Bazartserenen
dc.contributor.authorBottos, Eric M.en
dc.contributor.authorBoyer, Donal M.en
dc.contributor.authorBraun, Josephineen
dc.contributor.authorBrazelton, Williamen
dc.contributor.authorBrearley, Francis Q.en
dc.contributor.authorCampbell, Alexandra H.en
dc.contributor.authorCaporaso, J. Gregoryen
dc.contributor.authorCardona, Cesaren
dc.contributor.authorCarroll, JoLynnen
dc.contributor.authorCary, S. Craigen
dc.contributor.authorCasper, Brenda B.en
dc.contributor.authorCharles, Trevor C.en
dc.contributor.authorChu, Haiyanen
dc.contributor.authorClaar, Danielle C.en
dc.contributor.authorClark, Robert G.en
dc.contributor.authorClayton, Jonathan B.en
dc.contributor.authorClemente, Jose C.en
dc.contributor.authorCochran, Alyssaen
dc.contributor.authorColeman, Maureen L.en
dc.contributor.authorCollins, Gavinen
dc.contributor.authorColwell, Rita R.en
dc.contributor.authorContreras, Monicaen
dc.contributor.authorCrary, Benjamin B.en
dc.contributor.authorCreer, Simonen
dc.contributor.authorCristol, Daniel A.en
dc.contributor.authorCrump, Byron C.en
dc.contributor.authorCui, Duoyingen
dc.contributor.authorDaly, Sarah E.en
dc.contributor.authorDavalos, Lilianaen
dc.contributor.authorDawson, Russell D.en
dc.contributor.authorDefazio, Jenniferen
dc.contributor.authorDelsuc, Fredericen
dc.contributor.authorDionisi, Hebe M.en
dc.contributor.authorDominguez-Bello, Maria Gloriaen
dc.contributor.authorDowell, Robinen
dc.contributor.authorDubinsky, Eric A.en
dc.contributor.authorDunn, Peter O.en
dc.contributor.authorErcolini, Daniloen
dc.contributor.authorEspinoza, Robert E.en
dc.contributor.authorEzenwa, Vanessaen
dc.contributor.authorFenner, Nathalieen
dc.contributor.authorFindlay, Helen S.en
dc.contributor.authorFleming, Irma D.en
dc.contributor.authorFogliano, Vincenzoen
dc.contributor.authorForsman, Annaen
dc.contributor.authorFreeman, Chrisen
dc.contributor.authorFriedman, Elliot S.en
dc.contributor.authorGalindo, Giancarloen
dc.contributor.authorGarcia, Lizaen
dc.contributor.authorAlexandra Garcia-Amado, Mariaen
dc.contributor.authorGarshelis, Daviden
dc.contributor.authorGasser, Robin B.en
dc.contributor.authorGerdts, Gunnaren
dc.contributor.authorGibson, Molly K.en
dc.contributor.authorGifford, Isaacen
dc.contributor.authorGill, Ryan T.en
dc.contributor.authorGiray, Tugrulen
dc.contributor.authorGittel, Antjeen
dc.contributor.authorGolyshin, Peteren
dc.contributor.authorGong, Donglaien
dc.contributor.authorGrossart, Hans-Peteren
dc.contributor.authorGuyton, Kristinaen
dc.contributor.authorHaig, Sarah-Janeen
dc.contributor.authorHale, Vanessaen
dc.contributor.authorHall, Ross Stephenen
dc.contributor.authorHallam, Steven J.en
dc.contributor.authorHandley, Kim M.en
dc.contributor.authorHasan, Nur A.en
dc.contributor.authorHaydon, Shane R.en
dc.contributor.authorHickman, Jonathan E.en
dc.contributor.authorHidalgo, Glidaen
dc.contributor.authorHofmockel, Kirsten S.en
dc.contributor.authorHooker, Jeffen
dc.contributor.authorHulth, Stefanen
dc.contributor.authorHultman, Jennien
dc.contributor.authorHyde, Embrietteen
dc.contributor.authorIbanez-Alamo, Juan Diegoen
dc.contributor.authorJastrow, Julie D.en
dc.contributor.authorJex, Aaron R.en
dc.contributor.authorJohnson, L. Scotten
dc.contributor.authorJohnston, Eric R.en
dc.contributor.authorJoseph, Stephenen
dc.contributor.authorJurburg, Stephanie D.en
dc.contributor.authorJurelevicius, Diogoen
dc.contributor.authorKarlsson, Andersen
dc.contributor.authorKarlsson, Rogeren
dc.contributor.authorKauppinen, Sethen
dc.contributor.authorKellogg, Colleen T. E.en
dc.contributor.authorKennedy, Suzanne J.en
dc.contributor.authorKerkhof, Lee J.en
dc.contributor.authorKing, Gary M.en
dc.contributor.authorKling, George W.en
dc.contributor.authorKoehler, Anson V.en
dc.contributor.authorKrezalek, Monikaen
dc.contributor.authorKueneman, Jordan G.en
dc.contributor.authorLamendella, Reginaen
dc.contributor.authorLandon, Emily M.en
dc.contributor.authorLane-deGraaf, Kellyen
dc.contributor.authorLaRoche, Julieen
dc.contributor.authorLarsen, Peteren
dc.contributor.authorLaverock, Bonnieen
dc.contributor.authorLax, Simonen
dc.contributor.authorLentino, Miguelen
dc.contributor.authorLevin, Iris I.en
dc.contributor.authorLiancourt, Pierreen
dc.contributor.authorLiang, Wenjuen
dc.contributor.authorLinz, Alexandra M.en
dc.contributor.authorLipson, David A.en
dc.contributor.authorLiu, Yongqinen
dc.contributor.authorLladser, Manuel E.en
dc.contributor.authorLozada, Marianaen
dc.contributor.authorSpirito, Catherine M.en
dc.contributor.authorMacCormack, Walter P.en
dc.contributor.authorMacRae-Crerar, Auroraen
dc.contributor.authorMagris, Magdaen
dc.contributor.authorMartin-Platero, Antonio M.en
dc.contributor.authorMartin-Vivaldi, Manuelen
dc.contributor.authorMargarita Martinez, L.en
dc.contributor.authorMartinez-Bueno, Manuelen
dc.contributor.authorMarzinelli, Ezequiel M.en
dc.contributor.authorMason, Olivia U.en
dc.contributor.authorMayer, Gregory D.en
dc.contributor.authorMcDevitt-Irwin, Jamie M.en
dc.contributor.authorMcDonald, James E.en
dc.contributor.authorMcGuire, Krista L.en
dc.contributor.authorMcMahon, Katherine D.en
dc.contributor.authorMcMinds, Ryanen
dc.contributor.authorMedina, Monicaen
dc.contributor.authorMendelson, Joseph R., IIIen
dc.contributor.authorMetcalf, Jessica L.en
dc.contributor.authorMeyer, Folkeren
dc.contributor.authorMichelangeli, Fabianen
dc.contributor.authorMiller, Kimen
dc.contributor.authorMills, David A.en
dc.contributor.authorMinich, Jeremiahen
dc.contributor.authorMocali, Stefanoen
dc.contributor.authorMoitinho-Silva, Lucasen
dc.contributor.authorMoore, Annien
dc.contributor.authorMorgan-Kiss, Rachael M.en
dc.contributor.authorMunroe, Paulen
dc.contributor.authorMyrold, Daviden
dc.contributor.authorNeufeld, Josh D.en
dc.contributor.authorNi, Yingyingen
dc.contributor.authorNicol, Graeme W.en
dc.contributor.authorNielsen, Shaunen
dc.contributor.authorNissimov, Jozef I.en
dc.contributor.authorNiu, Kefengen
dc.contributor.authorNolan, Matthew J.en
dc.contributor.authorNoyce, Karenen
dc.contributor.authorO'Brien, Sarah L.en
dc.contributor.authorOkamoto, Norikoen
dc.contributor.authorOrlando, Ludovicen
dc.contributor.authorCastellano, Yadira Ortizen
dc.contributor.authorOsuolale, Olayinkaen
dc.contributor.authorOswald, Wyatten
dc.contributor.authorParnell, Jacoben
dc.contributor.authorPeralta-Sanchez, Juan M.en
dc.contributor.authorPetraitis, Peteren
dc.contributor.authorPfister, Catherineen
dc.contributor.authorPilon-Smits, Elizabethen
dc.contributor.authorPiombino, Paolaen
dc.contributor.authorPointing, Stephen B.en
dc.contributor.authorPollock, F. Josephen
dc.contributor.authorPotter, Caitlinen
dc.contributor.authorPrithiviraj, Bharathen
dc.contributor.authorQuince, Christopheren
dc.contributor.authorRani, Ashaen
dc.contributor.authorRanjan, Ravien
dc.contributor.authorRao, Subramanyaen
dc.contributor.authorRees, Andrew P.en
dc.contributor.authorRichardson, Milesen
dc.contributor.authorRiebesell, Ulfen
dc.contributor.authorRobinson, Carolen
dc.contributor.authorRockne, Karl J.en
dc.contributor.authorRodriguezl, Selena Marieen
dc.contributor.authorRohwer, Foresten
dc.contributor.authorRoundstone, Wayneen
dc.contributor.authorSafran, Rebecca J.en
dc.contributor.authorSangwan, Naseeren
dc.contributor.authorSanz, Virginiaen
dc.contributor.authorSchrenk, Matthewen
dc.contributor.authorSchrenzel, Mark D.en
dc.contributor.authorScott, Nicole M.en
dc.contributor.authorSeger, Rita L.en
dc.contributor.authorSeguin-Orlando, Andaineen
dc.contributor.authorSeldin, Lucyen
dc.contributor.authorSeyler, Lauren M.en
dc.contributor.authorShakhsheer, Baddren
dc.contributor.authorSheets, Gabriela M.en
dc.contributor.authorShen, Congcongen
dc.contributor.authorShi, Yuen
dc.contributor.authorShin, Hakdongen
dc.contributor.authorShogan, Benjamin D.en
dc.contributor.authorShutler, Daveen
dc.contributor.authorSiegel, Jeffreyen
dc.contributor.authorSimmons, Steveen
dc.contributor.authorSjoling, Saraen
dc.contributor.authorSmith, Daniel P.en
dc.contributor.authorSoler, Juan J.en
dc.contributor.authorSperling, Martinen
dc.contributor.authorSteinberg, Peter D.en
dc.contributor.authorStephens, Brenten
dc.contributor.authorStevens, Melita A.en
dc.contributor.authorTaghavi, Safiyhen
dc.contributor.authorTai, Veraen
dc.contributor.authorTait, Karenen
dc.contributor.authorTan, Chia L.en
dc.contributor.authorTas, Neslihanen
dc.contributor.authorTaylor, D. Leeen
dc.contributor.authorThomas, Torstenen
dc.contributor.authorTimling, Inaen
dc.contributor.authorTurner, Benjamin L.en
dc.contributor.authorUrich, Timen
dc.contributor.authorUrsell, Luke K.en
dc.contributor.authorvan der Lelie, Danielen
dc.contributor.authorVan Treuren, Williamen
dc.contributor.authorvan Zwieten, Lukasen
dc.contributor.authorVargas-Robles, Danielaen
dc.contributor.authorThurber, Rebecca Vegaen
dc.contributor.authorVitaglione, Paolaen
dc.contributor.authorWalker, Donald A.en
dc.contributor.authorWalters, William A.en
dc.contributor.authorWang, Shien
dc.contributor.authorWang, Taoen
dc.contributor.authorWeaver, Tomen
dc.contributor.authorWebster, Nicole S.en
dc.contributor.authorWehrle, Becken
dc.contributor.authorWeisenhorn, Pamelaen
dc.contributor.authorWeiss, Sophieen
dc.contributor.authorWerner, Jeffrey J.en
dc.contributor.authorWest, Kristinen
dc.contributor.authorWhitehead, Andrewen
dc.contributor.authorWhitehead, Susan R.en
dc.contributor.authorWhittingham, Linda A.en
dc.contributor.authorWillerslev, Eskeen
dc.contributor.authorWilliams, Allison E.en
dc.contributor.authorWood, Stephen A.en
dc.contributor.authorWoodhams, Douglas C.en
dc.contributor.authorYang, Yeqinen
dc.contributor.authorZaneveld, Jesseen
dc.contributor.authorZarraonaindia, Iratxeen
dc.contributor.authorZhang, Qikunen
dc.contributor.authorZhao, Hongxiaen
dc.contributor.departmentBiological Sciencesen
dc.date.accessioned2019-09-18T13:57:53Zen
dc.date.available2019-09-18T13:57:53Zen
dc.date.issued2017-11-23en
dc.description.abstractOur growing awareness of the microbial world's importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth's microbial diversity.en
dc.description.notesWe thank J. DeReus for management of information systems; J. Huntley and K. Jepsen for management of sequencing facilities; B. Erickson for administrative assistance; J. Lennon for discussions about macroecological theory; S. Peddada for assistance with effect size calculations; P. L. Buttigieg, C. Mungall, and D. Siegele for assistance with ontologies; A. Rose, A.-S. Roy, A. Bearquiver, B. Cohen, C. Tischer, C. Feh, D. Winkler, E. Jones, E. Angert, F. Blackwolf, G. Martin, H. Schunck, K. Hallinger, L. R. McGuinness, M. Muhling, M. Lombardo, R. Madsen, S. Bowatte, S. Romac, S. Garcia-Houchins, V. Harriman, and W. James for assistance with sample and/or metadata collection; and the following individuals for supporting the project's founding: A. Scyzrba, A. McHardy, A. Teske, A. Wilke, C. T. Brown, C. Brown, D. Huson, D. Field, D. Evers, D. Wendel, E. Glass, E. Kolke, F. Sun, F. O. Glockner,G. Kowalchuk, H.-P. Klenk, J. Tiedje, J. Gordon, J. Raes, J. Knight, J. Kostka, J. Heidelberg, J. Eisen, K. E. Wommack, K. Docherty, K. Keegan, K. Konstantindis, M. Bailey, M. Sullivan, N. Desai, N. Kyprides, N. Pace, P. Balaji, R. Gallery, R. Mackelprang, R. O'Dor, R. Ley, T. Vogel, T. Chen, and W. Feng. This work was supported by the John Templeton Foundation (grant ID 44000, Convergent Evolution of the Vertebrate Microbiome), the W. M. Keck Foundation (DT061413), Argonne National Laboratory (US Department of Energy contract DE-AC02-06CH11357), the Australian Research Council, the Tula Foundation, the Samuel Lawrence Foundation, and the Extreme Science and Engineering Discovery Environment (XSEDE, project number BIO150043), which is supported by National Science Foundation grant number ACI-1053575. Funding for L. R. T. was provided in part by NOAA's Atlantic Oceanographic and Meteorological Laboratory (AOML) and the Mississippi State University/NOAA Northern Gulf Institute. We thank MO BIO Laboratories, Luca Technologies, Eppendorf, Boreal Genomics, Illumina, Roche, and Integrated DNA Technologies for in-kind support at various phases of the project.en
dc.description.sponsorshipJohn Templeton Foundation [44000]; W. M. Keck Foundation [DT061413]; Argonne National Laboratory (US Department of Energy) [DE-AC02-06CH11357]; Australian Research Council; Tula Foundation; Samuel Lawrence Foundation; Extreme Science and Engineering Discovery Environment (XSEDE) [BIO150043]; National Science Foundation [ACI-1053575]; NOAA's Atlantic Oceanographic and Meteorological Laboratory (AOML); Mississippi State University/NOAA Northern Gulf Instituteen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1038/nature24621en
dc.identifier.eissn1476-4687en
dc.identifier.issn0028-0836en
dc.identifier.issue7681en
dc.identifier.pmid29088705en
dc.identifier.urihttp://hdl.handle.net/10919/93751en
dc.identifier.volume551en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleA communal catalogue reveals Earth's multiscale microbial diversityen
dc.title.serialNatureen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen

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