High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring

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dc.contributor.authorde Assis, Soniaen
dc.contributor.authorWärri, Annien
dc.contributor.authorCruz, M. Idaliaen
dc.contributor.authorLaja, Olusolaen
dc.contributor.authorTian, Yeen
dc.contributor.authorZhang, Baien
dc.contributor.authorWang, Yueen
dc.contributor.authorHuang, Tim H. M.en
dc.contributor.authorHilakivi-Clarke, Leenaen
dc.contributor.departmentElectrical and Computer Engineeringen
dc.date.accessioned2018-10-18T14:34:20Zen
dc.date.available2018-10-18T14:34:20Zen
dc.date.issued2012-01-01en
dc.description.abstractEnvironmental factors can influence one's susceptibility to cancer, but it is not clear whether such an influence extends beyond the directly exposed generations. Here, feeding pregnant rats with a high-fat diet or a hormone derivative, the authors observe increased breast cancer risk in up to three subsequent generations.en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1038/ncomms2058en
dc.identifier.issn20411723en
dc.identifier.pmid22968699en
dc.identifier.urihttp://hdl.handle.net/10919/85404en
dc.identifier.volume3en
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.rightsCreative Commons Attribution-NonCommercial-ShareAlike 3.0 Unporteden
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/en
dc.subject.meshAnimalsen
dc.subject.meshDietary Fats/adverse effectsen
dc.subject.meshEthinyl Estradiol/adverse effectsen
dc.subject.meshFemaleen
dc.subject.meshMammary Glands, Animal/pathologyen
dc.subject.meshMammary Neoplasms, Animal/chemically induceden
dc.subject.meshMaternal Exposure/adverse effectsen
dc.subject.meshPregnancyen
dc.subject.meshPrenatal Exposure Delayed Effectsen
dc.subject.meshRatsen
dc.subject.meshRats, Sprague-Dawleyen
dc.titleHigh-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspringen
dc.title.serialNature Communicationsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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