Escherichia coli-associated granulomatous colitis in a cat

dc.contributor.authorSafian, Alexander M.en
dc.contributor.authorBolton, Timothyen
dc.date.accessioned2021-02-19T19:39:55Zen
dc.date.available2021-02-19T19:39:55Zen
dc.date.issued2021en
dc.description.abstractA 6-year-old male castrated domestic shorthair cat was evaluated for a 6-month history of haematochezia, mucoid diarrhoea, tenesmus and rectal prolapse. Colonic histopathology revealed multifocal mucosal ulceration and lamina propria infiltration with large numbers of periodic acid-Schiff-positivemacrophages. Large clusters of intracellular Escherichia coli were confirmed with fluorescence in situ hybridization testing, similar to that seen in dogs with granulomatous colitis. An 8-week course of marbofloxacin resulted in resolution of clinical signs; however, recurrence occurred 4 weeks later. A 12-week course of marbofloxacin resulted in disease remission for which the cat still remains free of clinical signs (15 months). Escherichia coli-associated granulomatous colitis, although reported with rarity in this species, is an important infectious cause of chronic large intestinal disease in the cat.en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1002/vrc2.4en
dc.identifier.urihttp://hdl.handle.net/10919/102412en
dc.identifier.volume2021en
dc.language.isoenen
dc.publisherWileyen
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.titleEscherichia coli-associated granulomatous colitis in a caten
dc.title.serialVeterinary Record Case Reportsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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