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Risk Assessment in Chinese Hospitalized Patients Comparing the Padua and Caprini Scoring Algorithms

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dc.contributor.authorChen, Xiaolanen
dc.contributor.authorPan, Leien
dc.contributor.authorDeng, Huien
dc.contributor.authorZhang, Jingyuanen
dc.contributor.authorTong, Xinjieen
dc.contributor.authorHuang, Heen
dc.contributor.authorZhang, Minen
dc.contributor.authorHe, Jianlinen
dc.contributor.authorCaprini, Joseph A.en
dc.contributor.authorWang, Yongen
dc.date.accessioned2019-09-05T14:45:56Zen
dc.date.available2019-09-05T14:45:56Zen
dc.date.issued2018-12en
dc.description.abstractThe current venous thromboembolism (VTE) guidelines recommend all patients to be assessed for the risk of VTE using risk assessment models (RAMs). The study was to evaluate the performance of the Caprini and Padua RAMs among Chinese hospitalized patients. We reviewed data from 189 patients with deep venous thrombosis (DVT) and 201 non-DVT patients. Deep venous thrombosis risk factors were obtained from all patients. The sensitivity and specificity of the Caprini and Padua scores for all patients were calculated. The receiver operating curve (ROC) and the area under the ROC curve (AUC) were used to evaluate the performance of each score. We documented that age, acute infection, prothrombin time (PT), D-dimer, erythrocyte sedimentation rate, blood platelets, and anticoagulation were significantly associated with the occurrence of DVT (P < .05). These results were true for all medical and surgical patients group (G1), as well as the analysis of medical versus surgical patients (G2). Finally, analysis of the scores in patients with and without cancer was also done (G3). The Caprini has a higher sensitivity but a lower specificity than the Padua (P < .05). Caprini has a better predictive ability for the first 2 groups (P < .05). We found Caprini and Padua scores have a similar predictive value for patients with cancer (P > .05), while Caprini has a higher predictive ability for no cancer patients in G3 than Padua (P < .05). For Chinese hospitalized patients, Caprini has a higher sensitivity but a lower specificity than Padua. Overall, Caprini RAM has a better predictive ability than Padua RAM.en
dc.description.notesThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Research supported by Beijing Health Scientific Research Project (#2017-Jing17).en
dc.description.sponsorshipBeijing Health Scientific Research Project [2017-Jing17]en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1177/1076029618797465en
dc.identifier.eissn1938-2723en
dc.identifier.issn1076-0296en
dc.identifier.pmid30198321en
dc.identifier.urihttp://hdl.handle.net/10919/93391en
dc.identifier.volume24en
dc.language.isoenen
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectCaprinien
dc.subjectPaduaen
dc.subjectcomparisonen
dc.subjectChinese hospitalized patientsen
dc.titleRisk Assessment in Chinese Hospitalized Patients Comparing the Padua and Caprini Scoring Algorithmsen
dc.title.serialClinical and Applied Thrombosis-Hemostasisen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen

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