Controlling Magnetotactic Bacteria through an Integrated Nanofabricated Metallic Island and Optical Microscope Approach

dc.contributorVirginia Techen
dc.contributor.authorGonzalez, L. M.en
dc.contributor.authorRuder, W. C.en
dc.contributor.authorLeduc, P. R.en
dc.contributor.authorMessner, W. C.en
dc.contributor.departmentBiological Systems Engineeringen
dc.date.accessed2014-06-13en
dc.date.accessioned2014-06-16T14:11:24Zen
dc.date.available2014-06-16T14:11:24Zen
dc.date.issued2014-02-01en
dc.description.abstractHerein, we demonstrate the control of magnetotactic bacteria through the application of magnetic field gradients with real-time visualization. We accomplish this control by integrating a pair of macroscale Helmholtz coils and lithographically fabricated nanoscale islands composed of permalloy (Ni80Fe20). This system enabled us to guide and steer amphitrichous Magnetospirillum magneticum strain AMB-1 to specific location via magnetic islands. The geometries of the islands allowed us to have control over the specific magnetic field gradients on the bacteria. We estimate that magnetotactic bacteria located less than 1 mu m from the edge of a diamond shaped island experience a maximum force of approximately 34 pN, which engages the bacteria without trapping them. Our system could be useful for a variety of applications including magnetic fabrication, self-assembly, and probing the sensing apparatus of magnetotactic bacteria.en
dc.description.sponsorshipNational Science Foundation CMMI-1100430, CMMI-1160840, CPS-1135850, 0946825en
dc.description.sponsorshipOffice of Naval Research N000140910215en
dc.description.sponsorshipSloan Foundation Air Force Office of Scientific Research FA9550-13-1-01 08en
dc.format.mimetypeapplication/pdfen
dc.identifier.citationGonzalez, L. M.; Ruder, W. C.; Leduc, P. R.; Messner, W. C., "Controlling Magnetotactic Bacteria through an Integrated Nanofabricated Metallic Island and Optical Microscope Approach," Scientific Reports 4:4104, (2014). DOI: 10.1038/srep04104.en
dc.identifier.doihttps://doi.org/10.1038/srep04104en
dc.identifier.issn2045-2322en
dc.identifier.urihttp://hdl.handle.net/10919/48932en
dc.identifier.urlhttp://www.nature.com/srep/2014/140219/srep04104/full/srep04104.htmlen
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectMagnetic tweezersen
dc.subjectCell mechanicsen
dc.subjectLiving cellsen
dc.subjectForceen
dc.subjectBeadsen
dc.subjectMultidisciplinary sciencesen
dc.titleControlling Magnetotactic Bacteria through an Integrated Nanofabricated Metallic Island and Optical Microscope Approachen
dc.title.serialScientific Reportsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
srep04104.pdf
Size:
1.1 MB
Format:
Adobe Portable Document Format
Description:
Main article