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Endogenous giant viruses contribute to intraspecies genomic variability in the model green alga Chlamydomonas reinhardtii

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dc.contributor.authorMoniruzzaman, Mohammaden
dc.contributor.authorErazo-Garcia, Maria P.en
dc.contributor.authorAylward, Frank O.en
dc.date.accessioned2023-04-18T15:06:13Zen
dc.date.available2023-04-18T15:06:13Zen
dc.date.issued2022-11en
dc.description.abstractChlamydomonas reinhardtii is a unicellular eukaryotic alga that has been studied as a model organism for decades. Despite an extensive history as a model system, phylogenetic and genetic characteristics of viruses infecting this alga have remained elusive. We analyzed high-throughput genome sequence data of C. reinhardtii field isolates, and in six we discovered sequences belonging to endogenous giant viruses that reach up to several 100 kb in length. In addition, we have also discovered the entire genome of a closely related giant virus that is endogenized within the genome of Chlamydomonas incerta, the closest sequenced relative of C. reinhardtii. Endogenous giant viruses add hundreds of new gene families to the host strains, highlighting their contribution to the pangenome dynamics and interstrain genomic variability of C. reinhardtii. Our findings suggest that the endogenization of giant viruses may have important implications for structuring the population dynamics and ecology of protists in the environment.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1093/ve/veac102en
dc.identifier.eissn2057-1577en
dc.identifier.issue2en
dc.identifier.otherveac102en
dc.identifier.pmid36447475en
dc.identifier.urihttp://hdl.handle.net/10919/114539en
dc.identifier.volume8en
dc.language.isoenen
dc.publisherOxford University Pressen
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectendogenous virusen
dc.subjectchlaymodonas reinhardtiien
dc.subjectgiant virusen
dc.subjectimiterviralesen
dc.subjectgenome evolutionen
dc.titleEndogenous giant viruses contribute to intraspecies genomic variability in the model green alga Chlamydomonas reinhardtiien
dc.title.serialVirus Evolutionen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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