Potential Roles of Adropin in Central Nervous System: Review of Current Literature

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dc.contributor.authorShahjouei, Shimaen
dc.contributor.authorAnsari, Saeeden
dc.contributor.authorPourmotabbed, Tayebehen
dc.contributor.authorZand, Raminen
dc.date.accessioned2019-11-01T19:24:41Zen
dc.date.available2019-11-01T19:24:41Zen
dc.date.issued2016-06-27en
dc.description.abstractAdropin is a 4.9 kDa peptide that is important for maintenance of metabolic and non-metabolic homeostasis. It regulates glucose and fatty acid metabolism and is involved in endothelial cell function and endothelial nitric oxide (NO) synthase bioactivity as well as physical activity and motor coordination. Adropin is expressed in many tissues and organs including central nervous system (CNS). This peptide plays a crucial role in the development of various CNS disorders such as stroke, schizophrenia, bipolar disorder as well as Alzheimer's, Parkinson's, and Huntington's diseases. In this comprehensive review, the potential roles of adropin in cellular signaling pathways that lead to pathogenesis and/or treatment of CNS disorders will be discussed.en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.3389/fmolb.2016.00025en
dc.identifier.eissn2296-889Xen
dc.identifier.otherUNSP 25en
dc.identifier.pmid27446928en
dc.identifier.urihttp://hdl.handle.net/10919/95234en
dc.identifier.volume3en
dc.language.isoenen
dc.publisherFrontiersen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectadropinen
dc.subjectneurodegenerative diseaseen
dc.subjectneuroprotectionen
dc.subjectbiomarkeren
dc.subjectpredictoren
dc.subjecttherapeuticen
dc.subjectcellular signaling pathwaysen
dc.titlePotential Roles of Adropin in Central Nervous System: Review of Current Literatureen
dc.title.serialFrontiers in Molecular Biosciencesen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen

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Destination Area: Adaptive Brain and Behavior (ABB)