Modified live-attenuated vaccines (MLV) created by DNA shuffling against porcine reproductive and respiratory syndrome virus (PRRSV)

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorMeng, Xiang-Jinen
dc.contributor.inventorHuang, Yaoweien
dc.contributor.inventorNi, Yanyanen
dc.date.accessed2016-08-19en
dc.date.accessioned2016-08-24T17:55:26Zen
dc.date.available2016-08-24T17:55:26Zen
dc.date.filed2011-06-02en
dc.date.issued2015-09-15en
dc.description.abstractThe present invention provides a novel infectious cDNA clone of porcine reproductive and respiratory syndrome virus (PRRSV), particularly for PRRSV strain VR2385; an improved DNA-launched reverse genetics system for PRRSV; infectious chimeric PRRSV viruses generated through DNA shuffling; modified live-attenuated virus vaccines (MLV) using DNA shuffled chimeric viruses; chimeric viral proteins produced through shuffled chimeric viruses; PRRSV antigens and subunit vaccines based on shuffled chimeric viral proteins; and method of producing broadly protective PRRSV vaccines using DNA shuffling techniques.en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber13701729en
dc.identifier.patentnumber9132185en
dc.identifier.urihttp://hdl.handle.net/10919/72761en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/85/321/091/0.pdfen
dc.language.isoen_USen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcA61K39/12en
dc.subject.cpcA61K2039/5254en
dc.subject.cpcA61K2039/552en
dc.subject.cpcC12N7/00en
dc.subject.cpcC12N2770/10034en
dc.subject.cpcC12N2770/10052en
dc.subject.uspc1/1en
dc.titleModified live-attenuated vaccines (MLV) created by DNA shuffling against porcine reproductive and respiratory syndrome virus (PRRSV)en
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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