The PLOS ONE Synthetic Biology Collection: Six Years and Counting

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dc.contributorVirginia Techen
dc.contributor.authorPeccoud, Jeanen
dc.contributor.authorIsalan, Marken
dc.date.accessed2014-05-06en
dc.date.accessioned2014-06-17T20:12:08Zen
dc.date.available2014-06-17T20:12:08Zen
dc.date.issued2012-08-15en
dc.description.abstractSince it was launched in 2006, PLOS ONE has published over fifty articles illustrating the many facets of the emerging field of synthetic biology. This article reviews these publications by organizing them into broad categories focused on DNA synthesis and assembly techniques, the development of libraries of biological parts, the use of synthetic biology in protein engineering applications, and the engineering of gene regulatory networks and metabolic pathways. Finally, we review articles that describe enabling technologies such as software and modeling, along with new instrumentation. In order to increase the visibility of this body of work, the papers have been assembled into the PLOS ONE Synthetic Biology Collection (www.ploscollections.org/synbio). Many of the innovative features of the PLOS ONE web site will help make this collection a resource that will support a lively dialogue between readers and authors of PLOS ONE synthetic biology papers. The content of the collection will be updated periodically by including relevant articles as they are published by the journal. Thus, we hope that this collection will continue to meet the publishing needs of the synthetic biology community.en
dc.description.sponsorshipJP is supported by National Science Foundation Awards 0850100 and 0963988 and by grants R01-GM078989 and R01-GM095955 from the National Institutes of Health. MI is funded by FP7 ERC 201249 ZINC-HUBS, Ministerio de Ciencia e Innovacion grant MICINN BFU2010-17953 and the MEC-EMBL agreement. The funders had no role in the preparation of the manuscript.en
dc.identifier.citationPeccoud J, Isalan M. The PLOS ONE Synthetic Biology Collection: Six Years and Counting. PLoS One. 2012;7(8):e43231.  http://dx.doi.org/10.1371%2Fjournal.pone.0043231en
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0043231en
dc.identifier.issn1932-6203en
dc.identifier.urihttp://hdl.handle.net/10919/48995en
dc.identifier.urlhttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0043231en
dc.language.isoen_USen
dc.publisherPublic Library of Scienceen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectCloningen
dc.subjectEngineering and technologyen
dc.subjectGene regulatory networksen
dc.subjectMacromolecular engineeringen
dc.subjectProtein engineeringen
dc.subjectSequence motif analysisen
dc.subjectSynthetic bioengineeringen
dc.subject"Synthetic biologyen
dc.titleThe PLOS ONE Synthetic Biology Collection: Six Years and Countingen
dc.title.serialPLoS ONEen
dc.typeArticle - Refereeden

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