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Synthesis and Toxicity of Lipid-Coated-Titanium Oxide Nanoparticles

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dc.contributor.authorHollingsworth, Louisen
dc.contributor.authorConduff, Josephen
dc.contributor.authorBalzer, Conneren
dc.contributor.authorTran, Sieuen
dc.contributor.authorHamid, Waqasen
dc.contributor.authorRakes, Laurenen
dc.contributor.editorStinson-Bagby, Kellyen
dc.date.accessioned2019-06-19T21:11:49Zen
dc.date.available2019-06-19T21:11:49Zen
dc.date.issued2015-01-01en
dc.description.abstractNanoparticles have a broad range of applications in novel materials and consumer products. Due to the unique properties of nanoscale materials, the toxic effects of various nanoparticles are largely unknown. Surface modifications to nanoparticles, such as membrane or lipid coatings, may reduce immunogenicity and environmental toxicity, but these effects remain largely uncharacterized. The synthesis of lipid-coated titanium oxide nanoparticles was optimized and toxicity was evaluated. Thermogravimetric analysis showed that 5 μM of tricarboxylic amphiphile sufficiently generated uniformly coated nanoparticles. Toxicity studies on Zea mays (corn) revealed that uncoated titanium oxide nanoparticles exhibited phytotoxicity, while lipid-coated nanoparticles had effects resembling deionized water. Scanning electron microscopy displayed visual evidence of nanoparticle absorption into the corn seedlings in experimental groups.en
dc.format.extent7 pagesen
dc.format.extent636.29 KBen
dc.format.mimetypeapplication/pdfen
dc.format.mimetypeapplication/zipen
dc.identifier.citationHollingsworth, L.R., Conduff, J.H., Balzer, C.J., Tran, S.K., Hamid, W. and Rakes, L.E., 2015. Synthesis and Toxicity of Lipid-Coated-Titanium Oxide Nanoparticles. Journal of Undergraduate Materials Research, 5. DOI: http://doi.org/10.21061/jumr.v5i0.1533en
dc.identifier.doihttps://doi.org/10.21061/jumr.v5i0.1533en
dc.identifier.eissn2578-9570en
dc.identifier.issn1934-7677en
dc.identifier.issue1en
dc.identifier.urihttp://hdl.handle.net/10919/90357en
dc.identifier.volume5en
dc.language.isoenen
dc.publisherVirginia Tech Department of Materials Science and Engineeringen
dc.rightsIn Copyrighten
dc.rights.holderVirginia Tech Department of Materials Science and Engineeringen
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectMaterials Scienceen
dc.subjectNanoparticlesen
dc.titleSynthesis and Toxicity of Lipid-Coated-Titanium Oxide Nanoparticlesen
dc.title.serialJournal of Undergraduate Materials Researchen
dc.typeArticleen
dc.type.dcmitypeTexten

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