Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa
dc.contributor | Virginia Tech | en |
dc.contributor.author | McAdams, Carrie J. | en |
dc.contributor.author | Jeon-Slaughter, Haekyung | en |
dc.contributor.author | Evans, Siobahn | en |
dc.contributor.author | Lohrenz, Terry | en |
dc.contributor.author | Montague, P. Read | en |
dc.contributor.author | Krawczyk, Daniel C. | en |
dc.date.accessioned | 2017-09-07T14:38:18Z | en |
dc.date.available | 2017-09-07T14:38:18Z | en |
dc.date.issued | 2016-06-27 | en |
dc.description.abstract | Anorexia nervosa (AN) is a severe mental illness characterized by problems with self-perception. Whole-brain neural activations in healthy women, women with AN and women in long-term weight recovery following AN were compared using two functional magnetic resonance imaging tasks probing different aspects of self-perception. The Social Identity-V2 task involved consideration about oneself and others using socially descriptive adjectives. Both the ill and weight-recovered women with AN engaged medial prefrontal cortex less than healthy women for self-relevant cognitions, a potential biological trait difference. Weight-recovered women also activated the inferior frontal gyri and dorsal anterior cingulate more for direct self-evaluations than for reflected self-evaluations, unlike both other groups, suggesting that recovery may include compensatory neural changes related to social perspectives. The Faces task compared viewing oneself to a stranger. Participants with AN showed elevated activity in the bilateral fusiform gyri for self-images, unlike the weight-recovered and healthy women, suggesting cognitive distortions about physical appearance are a state rather than trait problem in this disease. Because both ill and recovered women showed neural differences related to social self-perception, but only recovered women differed when considering social perspectives, these neurocognitive targets may be particularly important for treatment. | en |
dc.identifier.doi | https://doi.org/10.1093/scan/nsw092 | en |
dc.identifier.issue | 11 | en |
dc.identifier.uri | http://hdl.handle.net/10919/78818 | en |
dc.identifier.volume | 11 | en |
dc.language.iso | en_US | en |
dc.publisher | Oxford | en |
dc.rights | In Copyright | en |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en |
dc.subject | eating disorders | en |
dc.subject | medial prefrontal cortex | en |
dc.subject | self-reflection | en |
dc.subject | fMRI | en |
dc.subject | psychiatry | en |
dc.title | Neural differences in self-perception during illness and after weight-recovery in anorexia nervosa | en |
dc.title.serial | Social Cognitive and Affective Neuroscience | en |
dc.type | Article - Refereed | en |
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