B/B-like fragment targeting for the purposes of photodynamic therapy and medical imaging

dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorStorrie, Brianen
dc.contributor.inventorTarrago-Trani, Maria T.en
dc.contributor.inventorEnglish, Samen
dc.date.accessed2016-08-19en
dc.date.accessioned2016-08-24T17:54:23Zen
dc.date.available2016-08-24T17:54:23Zen
dc.date.filed2001-06-29en
dc.date.issued2003-10-07en
dc.description.abstractThe invention provides compositions and methods for use in delivering a substance of interest to a targeted cell. The substance of interest is associated with a targeting fragment of a toxin molecule or a lectin that specifically binds to a cell surface receptor, such as the B subunit of an A/B type toxin molecule. The substance of interest may be a photosensitizing agent, in which case the cell (e.g. a cancer cell) may be killed by exposure to light after delivery of the agent. Alternatively, the substance of interest may be a visualizing agent that enhances visualization of the targeted cell.en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber9894896en
dc.identifier.patentnumber6631283en
dc.identifier.urihttp://hdl.handle.net/10919/72477en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/83/312/066/0.pdfen
dc.language.isoen_USen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcA61K41/0057en
dc.subject.cpcA61K41/0071en
dc.subject.cpcA61K47/48261en
dc.subject.cpcA61K49/0002en
dc.subject.cpcA61K49/04en
dc.subject.cpcA61K49/085en
dc.subject.cpcA61K49/14en
dc.subject.uspc128/898en
dc.subject.uspcother600/407en
dc.subject.uspcother600/1en
dc.subject.uspcother600/3en
dc.titleB/B-like fragment targeting for the purposes of photodynamic therapy and medical imagingen
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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