Transition metals as anti-tumoral agents: some structure-function relationships of the platinum group metals

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dc.contributor.authorFlynn, Allisonen
dc.contributor.committeechairMerola, Joseph S.en
dc.contributor.committeememberNiehaus, Walter G. Jr.en
dc.contributor.committeememberBrewer, Karen J.en
dc.contributor.departmentChemistryen
dc.date.accessioned2014-03-14T21:30:23Zen
dc.date.adate2010-03-02en
dc.date.available2014-03-14T21:30:23Zen
dc.date.issued1994-06-05en
dc.date.rdate2010-03-02en
dc.date.sdate2010-03-02en
dc.description.abstract<p>Since the discovery that cis-diamminedichloroplatinum (II) possessed great antitumor properties, researchers have been synthesizing and screening metal coordination complexes for their potential anti-tumor activity. Hundreds of compounds have been tested, and few compounds possessed anti-tumor activity. This paper examines how the physical and chemical properties of complexes of the platinum group metals affect their toxicity and anti-tumor activity.</p>en
dc.description.degreeMaster of Scienceen
dc.format.extentx, 62 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-03022010-020016en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-03022010-020016/en
dc.identifier.urihttp://hdl.handle.net/10919/41305en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V851_1994.F596.pdfen
dc.relation.isformatofOCLC# 31140061en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V851 1994.F596en
dc.subject.lcshAntineoplastic agentsen
dc.subject.lcshPlatinum groupen
dc.titleTransition metals as anti-tumoral agents: some structure-function relationships of the platinum group metalsen
dc.typeMaster's projecten
dc.type.dcmitypeTexten
thesis.degree.disciplineChemistryen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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