Transpulmonary ultrasound dilution is an acceptable technique for cardiac output measurement in anesthetized pigs

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dc.contributor.authorParanjape, Vaidehi V.en
dc.contributor.authorShih, Andre C.en
dc.contributor.authorGarcia-Pereira, Fernando L.en
dc.contributor.authorSaksena, Siddharthen
dc.date.accessioned2022-12-15T13:42:48Zen
dc.date.available2022-12-15T13:42:48Zen
dc.date.issued2022-06en
dc.description.abstractOBJECTIVE To evaluate cardiac output (CO) measurements using transpulmonary ultrasound (TPUD) technology and compare results with those of the gold standard, pulmonary arterial catheter thermodilution (PACTD), in 6 healthy anesthetized pigs during acute hemodynamic changes caused by manipulation of the blood volume. ANIMALS 6 healthy male Landrace pigs. PROCEDURES Over a period of 1 week, pigs were anesthetized with isoflurane, mechanically ventilated, and underwent instrumentation in dorsal recumbency. They were subjected to sequential experimental states during which the blood volume was manipulated so that the animals transitioned from normovolemia to hypovolemia (20% and 40% of blood volume depletion), back to normovolemia (autologous blood transfusion), and then to hypervolemia (following colloid bolus). During each volume state, CO measurements were compared between TPUD and PACTD.en
dc.description.notesThis study was a part of an extensive hemodynamic research project supported by University of Florida research funds. The authors declare that there were no conflicts of interest. The authors thank Savannah Mauragis for her assistance with creating graphical Figures 1 and 2 for this manuscript.en
dc.description.sponsorshipUniversity of Florida research fundsen
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.2460/ajvr.21.11.0189en
dc.identifier.eissn1943-5681en
dc.identifier.issn0002-9645en
dc.identifier.issue6en
dc.identifier.pmid35524964en
dc.identifier.urihttp://hdl.handle.net/10919/112902en
dc.identifier.volume83en
dc.language.isoenen
dc.publisherAmerican Veterinary Medical Associationen
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectvelocity dilutionen
dc.subjectlithium dilutionen
dc.subjectprecision statisticsen
dc.subjectthermodilutionen
dc.subjectechocardiographyen
dc.subjecttechnologyen
dc.subjectagreementen
dc.subjectbiasen
dc.titleTranspulmonary ultrasound dilution is an acceptable technique for cardiac output measurement in anesthetized pigsen
dc.title.serialAmerican Journal of Veterinary Researchen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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