Control and Manipulation of Microfluidic Flow via Elastic Deformations

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dc.contributorVirginia Tech. Engineering Science and Mechanics Departmenten
dc.contributorPrinceton University. Department of Mechanical & Aerospace Engineeringen
dc.contributor.authorHolmes, Douglas P.en
dc.contributor.authorTavakol, Behrouzen
dc.contributor.authorFroehlicher, Guillaumeen
dc.contributor.authorStone, Howard A.en
dc.contributor.departmentBiomedical Engineering and Mechanicsen
dc.date.accessed2015-04-17en
dc.date.accessioned2015-04-20T22:11:56Zen
dc.date.available2015-04-20T22:11:56Zen
dc.date.issued2013-05-08en
dc.description.abstractWe utilize elastic deformations via mechanical actuation to control and direct fluid flow within a flexible microfluidic device. The device consists of a microchannel with a flexible arch prepared by the buckling of a thin elastic film. The deflection of the arch can be predicted and controlled using the classical theory of Euler buckling. The fluid flow rate is then controlled by coupling the elastic deformation of the arch to the gap within the microchannel, and the results compared well with analytical predictions from a perturbation calculation and numerical simulations. We demonstrate that placement of these flexible valves in series enables directed flow towards regions of externally applied mechanical stress. The simplicity of the experimental approach provides a general design for advanced functionality in portable microfluidics, self-healing devices, and in situ diagnostics.en
dc.description.sponsorshipUnited States. Army Research Office. Multidisciplinary University Research Initiative (MURI) - #W911NF-09-1-0476en
dc.format.mimetypeapplication/pdfen
dc.identifier.citationHolmes, D. P., Tavakol, B., Froehlicher, G., & Stone, H. A. (2013). Control and manipulation of microfluidic flow via elastic deformations. Soft Matter, 9(29), 7049-7053. doi: 10.1039/C3SM51002Fen
dc.identifier.doihttps://doi.org/10.1039/C3SM51002Fen
dc.identifier.issn1744-683Xen
dc.identifier.urihttp://hdl.handle.net/10919/51721en
dc.identifier.urlhttp://pubs.rsc.org/en/content/articlelanding/2013/sm/c3sm51002fen
dc.language.isoen_USen
dc.publisherThe Royal Society of Chemistryen
dc.relation.ispartofseriesEmerging Investigatorsen
dc.relation.urihttp://pubs.rsc.org/en/journals/journalissues/smen
dc.rightsCreative Commons Attribution-NonCommercial 3.0 Unporteden
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/en
dc.subjectElastic deformationsen
dc.subjectMicrofluidic flowen
dc.subjectMicrofluidic devicesen
dc.titleControl and Manipulation of Microfluidic Flow via Elastic Deformationsen
dc.title.serialSoft Matteren
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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