Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties

dc.contributor.authorWang, Z. G.en
dc.contributor.authorLiu, Y.en
dc.contributor.authorWang, G.en
dc.contributor.authorSun, L. Z.en
dc.contributor.departmentSchool of Biomedical Engineering and Sciencesen
dc.date.accessioned2017-09-18T10:01:45Zen
dc.date.available2017-09-18T10:01:45Zen
dc.date.issued2009-07-09en
dc.date.updated2017-09-18T10:01:44Zen
dc.description.abstractElastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex breast tissue properties. The elastic parameters are estimated by optimally minimizing the difference between the computed forces and experimental measures. A nonlinear adjoint method is derived to calculate the gradient of the objective function, which significantly enhances the numerical efficiency and stability. Simulations are conducted on a three-dimensional heterogeneous breast phantom extracting from real imaging including fatty tissue, glandular tissue, and tumors. Anexponential-form of nonlinear material model is applied. The effect of noise is taken into account.Results demonstrate that the proposed nonlinear method opens the door toward nonlinear elastographyand provides guidelines for future development and clinical application in breast cancer study.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationZ. G. Wang, Y. Liu, G. Wang, and L. Z. Sun, “Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties,” International Journal of Biomedical Imaging, vol. 2009, Article ID 406854, 9 pages, 2009. doi:10.1155/2009/406854en
dc.identifier.doihttps://doi.org/10.1155/2009/406854en
dc.identifier.urihttp://hdl.handle.net/10919/79055en
dc.language.isoenen
dc.publisherHindawien
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.holderCopyright © 2009 Z. G. Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleElastography Method for Reconstruction of Nonlinear Breast Tissue Propertiesen
dc.title.serialInternational Journal of Biomedical Imagingen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
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