Molecular preservation in mammoth bone and variation based on burial environment

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dc.contributor.authorColleary, Caitlinen
dc.contributor.authorLamadrid, Hector M.en
dc.contributor.authorO'Reilly, Shane S.en
dc.contributor.authorDolocan, Andreien
dc.contributor.authorNesbitt, Sterling J.en
dc.contributor.departmentGeosciencesen
dc.date.accessioned2021-05-28T14:40:59Zen
dc.date.available2021-05-28T14:40:59Zen
dc.date.issued2021-01-29en
dc.description.abstractBiomolecules preserved in fossils are expanding our understanding of the biology and evolution of ancient animals. Molecular taphonomy seeks to understand how these biomolecules are preserved and how they can be interpreted. So far, few studies on molecular preservation have considered burial context to understand its impact on preservation or the potentially complementary information from multiple biomolecular classes. Here, we use mass spectrometry and other analytical techniques to detect the remains of proteins and lipids within intact fossil mammoth bones of different ages and varied depositional setting. By combining these approaches, we demonstrate that endogenous amino acids, amides and lipids can preserve well in fossil bone. Additionally, these techniques enable us to examine variation in preservation based on location within the bone, finding dense cortical bone better preserves biomolecules, both by slowing the rate of degradation and limiting the extent of exogenous contamination. Our dataset demonstrates that biomolecule loss begins early, is impacted by burial environment and temperature, and that both exogenous and endogenous molecular signals can be both present and informative in a single fossil.en
dc.description.notesFunding for this project was from a series of graduate student grants awarded to CC: Virginia Space Grant Consortium Graduate STEM Research Fellowship, Stan Wood Award (The Paleontological Association), a graduate student research grant (Geological Society of America), Dr. Larry Agenbroad Legacy Fund for Research (The Mammoth Site of Hot Springs, SD), Charles J. Gose Jr. Research Scholarship (Virginia Tech, Department of Geosciences) and from the graduate research development fund (Virginia Tech, Graduate School Assembly). SO'R acknowledges funding from Irish Research Council International Career Development Fellowships in Science, Engineering and Technology-Co-funded by the European Commission Marie Curie Actions Programme (Grant number 291760).en
dc.description.sponsorshipVirginia Space Grant Consortium Graduate STEM Research Fellowship; Paleontological Association; Geological Society of America; The Mammoth Site of Hot Springs, SD; Virginia Tech, Department of Geosciences; Virginia Tech, Graduate School Assembly; Irish Research CouncilIrish Research Council for Science, Engineering and Technology; European Commission Marie Curie Actions Programme [291760]en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1038/s41598-021-81849-6en
dc.identifier.issn2045-2322en
dc.identifier.issue1en
dc.identifier.other2662en
dc.identifier.pmid33514821en
dc.identifier.urihttp://hdl.handle.net/10919/103545en
dc.identifier.volume11en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleMolecular preservation in mammoth bone and variation based on burial environmenten
dc.title.serialScientific Reportsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen

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