Equine Protozoal Myeloencephalitis: An Updated Consensus Statement with a Focus on Parasite Biology, Diagnosis, Treatment, and Prevention

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dc.contributor.authorReed, S. M.en
dc.contributor.authorFurr, M. O.en
dc.contributor.authorHowe, D. K.en
dc.contributor.authorJohnson, A. L.en
dc.contributor.authorMacKay, R. J.en
dc.contributor.authorMorrow, J. K.en
dc.contributor.authorPusterla, N.en
dc.contributor.authorWitonsky, Sharon G.en
dc.date.accessioned2019-08-08T12:44:50Zen
dc.date.available2019-08-08T12:44:50Zen
dc.date.issued2016-03en
dc.description.abstractEquine protozoal myeloencephalitis (EPM) remains an important neurologic disease of horses. There are no pathognomonic clinical signs for the disease. Affected horses can have focal or multifocal central nervous system (CNS) disease. EPM can be difficult to diagnose antemortem. It is caused by either of 2 parasites, Sarcocystis neurona and Neospora hughesi, with much less known about N. hughesi. Although risk factors such as transport stress and breed and age correlations have been identified, biologic factors such as genetic predispositions of individual animals, and parasite-specific factors such as strain differences in virulence, remain largely undetermined. This consensus statement update presents current published knowledge of the parasite biology, host immune response, disease pathogenesis, epidemiology, and risk factors. Importantly, the statement provides recommendations for EPM diagnosis, treatment, and prevention.en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1111/jvim.13834en
dc.identifier.eissn1939-1676en
dc.identifier.issn0891-6640en
dc.identifier.issue2en
dc.identifier.pmid26857902en
dc.identifier.urihttp://hdl.handle.net/10919/92884en
dc.identifier.volume30en
dc.language.isoenen
dc.publisherAmerican College of Veterinary Internal Medicineen
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectEncephalitisen
dc.subjectEquine myeloencephalopathyen
dc.subjectEquine neurologicen
dc.subjectEquine protozoal diseaseen
dc.subjectMyelitisen
dc.subjectNeospora hughesien
dc.subjectSarcocystis neuronaen
dc.titleEquine Protozoal Myeloencephalitis: An Updated Consensus Statement with a Focus on Parasite Biology, Diagnosis, Treatment, and Preventionen
dc.title.serialJournal of Veterinary Internal Medicineen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen

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